| Common Name: | METRONIDAZOLE |
| Manufacturer: | RESEARCH PRODUCTS INTERNATIONAL |
| SDS Revision Date: | 9/20/2017 |
| SDS Format: | No Format Specified |
| Item Number(s): | 30TZ37 |
| Manufacturer Model Number(s): |
SDS Table of Contents
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PRODUCT SAFETY DATA SHEET
RESEARCH PRODUCTS INTERNATIONAL
ISSUE DATE: 12/15/14
REV.: 1
REV DATE: 09/20/17
DOCUMENT #: F/RPI/QC 7.7.3-02
PRODUCT NAME: METRONIDAZOLE
RPI ITEM NO: M81000
| SECTION 1 - CHEMICAL IDENTIFICATION |  |
PRODUCT NAME: METRONIDAZOLE
RPI CATALOG #: M81000
SUPPLIER'S NAME: RESEARCH PRODUCTS INTERNATIONAL CORP.
SUPPLIERS ADDRESS:
410 N BUSINESS CENTER DRIVE MOUNT PROSPECT,
IL 60056
EMERGENCY CONTACT: 1-800-424-9300
OTHER INFORMATION: 847-635-7330
| SECTION 2 - HAZARDS IDENTIFICATION | |
2.1 CLASSIFICATION OF THE SUBSTANCE OR MIXTURE:
GHS CLASSIFICATION IN ACCORDANCE WITH 29 CFR 1910 (OSHA HCS):
H351:
CARCINOGENICITY: CATEGORY 2
H371:
SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE: CATEGORY 2
2.2 GHS LABEL ELEMENTS, INCLUDING HAZARD AND PRECAUTIONARY STATEMENT(S):
PICTOGRAM: HEALTH HAZARD
SIGNAL WORD: WARNING
HAZARD STATEMENT(S):
H351: SUSPECTED OF CAUSING CANCER
H371: MAY CAUSE DAMAGE TO ORGANS.
PREVENTION, RESPONSE, STORAGE AND DISPOSAL PRECAUTIONARY STATEMENT(S):
P201: OBTAIN SPECIAL INSTRUCTIONS BEFORE USE.
P202:
DO NOT HANDLE UNTIL ALL SAFETY PRECAUTIONS HAVE BEEN READ AND UNDERSTOOD.
P260: DO NOT BREATHE DUST/FUME/GAS/MIST/VAPORS/SPRAY.
P264: WASH SKIN THOROUGHLY AFTER HANDLING
P270: DO NOT EAT, DRINK OR SMOKE WHEN USING THIS PRODUCT.
P280:
WEAR PROTECTIVE GLOVES/ PROTECTIVE CLOTHING/ EYE PROTECTION/ FACE
PROTECTION.
P308 + P311:
IF EXPOSED OR CONCERNED: CALL A POISON CENTER OR DOCTOR/ PHYSICIAN
P308 + P313:
IF EXPOSED OR CONCERNED: GET MEDICAL ADVICE/ ATTENTION.
P405: STORE LOCKED UP.
P501: DISPOSE OF CONTENTS/ CONTAINER TO AN APPROVED WASTE DISPOSAL PLANT.
| SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS | |
CAS NUMBER: 443-48-1
EINECS NUMBER: 207-136-1
FORMULA: C6H9N3O3
MOLECULAR WEIGHT: 171.2 G/MOL
| SECTION 4 - FIRST-AID MEASURES | |
4.1 DESCRIPTION OF FIRST AID MEASURES:
GENERAL ADVICE: CONSULT A DOCTOR AND SHOW THIS SAFETY DATA SHEET.
I. IF INHALED:
REMOVE TO FRESH AIR AND MONITOR BREATHING. IF BREATHING BECOMES DIFFICULT,
GIVE OXYGEN. IF BREATHING STOPS, GIVE ARTIFICIAL RESPIRATION. CONSULT A
DOCTOR.
II. IN CASE OF SKIN CONTACT:
IMMEDIATELY WASH SKIN WITH COPIOUS AMOUNTS OF SOAP AND WATER FOR AT LEAST
15 MINUTES. REMOVE CONTAMINATED CLOTHING AND SHOES AND WASH BEFORE REUSE.
CONSULT A DOCTOR.
III. IN CASE OF EYE CONTACT:
FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. CONSULT A
DOCTOR.
IV. IF SWALLOWED:
RINSE MOUTH WITH WATER. DO NOT INDUCE VOMITING UNLESS DIRECTED TO DO SO
BY MEDICAL PERSONNEL. NEVER GIVE ANYTHING BY MOUTH TO AN UNCONSCIOUS
PERSON. CONSULT A DOCTOR.
4.2 MOST IMPORTANT SYMPTOMS AND EFFECTS, BOTH ACUTE AND DELAYED:
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL AND TOXICOLOGICAL
PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
4.3 INDICATION OF IMMEDIATE MEDICAL ATTENTION AND SPECIAL TREATMENT NEEDED:
SHOW THIS SAFETY DATA SHEET TO THE DOCTOR IN ATTENDANCE. IMMEDIATE MEDICAL
ATTENTION IS REQUIRED.
| SECTION 5 - FIRE FIGHTING MEASURES | |
5.1 EXTINGUISHING MEDIA:
SUITABLE EXTINGUISHING MEDIA:
USE WATER SPRAY, ALCOHOL-RESISTANT FOAM, DRY CHEMICAL OR CARBON DIOXIDE
5.2 SPECIAL HAZARDS ARISING FROM THE SUBSTANCE OR MIXTURE:
CARBON DIOXIDE (CO2) NITROGEN OXIDES (NOX)
5.3 PRECAUTIONS FOR FIRE-FIGHTERS:
WEAR SUITABLE PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES
AND SELF-CONTAINED BREATHING APPARATUS.
5.4 FURTHER INFORMATION: NO DATA AVAILABLE
| SECTION 6 - ACCIDENTAL RELEASE MEASURES | |
6.1 PERSONAL PRECAUTIONS, PROTECTIVE EQUIPMENT AND EMERGENCY PROCEDURES:
DO NOT TAKE ACTION WITHOUT SUITABLE PROTECTIVE CLOTHING - SEE SECTION 8
OF SDS. EVACUATE PERSONNEL TO SAFE AREAS. ENSURE ADEQUATE VENTILATION.
AVOID BREATHING VAPORS, MIST, DUST OR GAS.
6.2 ENVIRONMENTAL PRECAUTIONS: DO NOT LET PRODUCT ENTER DRAINS.
6.3 METHODS AND MATERIALS FOR CONTAINMENT AND CLEANING UP:
COVER SPILLAGE WITH SUITABLE ABSORBENT MATERIAL. USING NON-SPARK TOOLS,
SWEEP UP MATERIAL AND PLACE IN AN APPROPRIATE CONTAINER. DECONTAMINATE
SPILL SITE WITH 10% CAUSTIC SOLUTION AND VENTILATE AREA UNTIL AFTER
DISPOSAL IS COMPLETE. HOLD ALL MATERIAL FOR APPROPRIATE DISPOSAL AS
DESCRIBED UNDER SECTION 13 OF SDS.
6.4 REFERENCE TO OTHER SECTIONS:
FOR REQUIRED PPE SEE SECTION 8. FOR DISPOSAL SEE SECTION 13.
| SECTION 7 - HANDLING AND STORAGE | |
7.1 PRECAUTIONS FOR SAFE HANDLING:
USE IN A CHEMICAL FUME HOOD, WITH AIR SUPPLIED BY AN INDEPENDENT SYSTEM.
AVOID INHALATION, CONTACT WITH EYES, SKIN AND CLOTHING. AVOID THE FORMATION
OF DUST AND AEROSOLS. USE IN A WELL-VENTILATED AREA. KEEP AWAY FROM SOURCES
OF IGNITION. AVOID PROLONGED OR REPEATED EXPOSURE.
7.2 CONDITIONS FOR SAFE STORAGE, INCLUDING ANY INCOMPATIBILITIES:
STORE IN COOL, WELL-VENTILATED AREA. KEEP AWAY FROM DIRECT SUNLIGHT. KEEP
CONTAINER TIGHTLY SEALED UNTIL READY FOR USE. STORE AT ROOM TEMPERATURE.
7.3 SPECIFIC END USE(S):
USE IN A LABORATORY FUME HOOD WHERE POSSIBLE. REFER TO EMPLOYER'S COSHH
RISK ASSESSMENT.
| SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION | |
8.1 CONTROL PARAMETERS:
COMPONENTS WITH WORKPLACE CONTROL PARAMETERS:
CONTAINS NO SUBSTANCES WITH OCCUPATIONAL EXPOSURE LIMIT VALUES.
8.2 EXPOSURE CONTROLS:
I. APPROPRIATE ENGINEERING CONTROLS:
USE IN A FUME HOOD WHERE APPLICABLE. ENSURE ALL ENGINEERING MEASURES
DESCRIBED UNDER SECTION 7 OF SDS ARE IN PLACE. ENSURE LABORATORY IS
EQUIPPED WITH A SAFETY SHOWER AND EYE WASH STATION.
8.3 PERSONAL PROTECTIVE EQUIPMENT:
I. EYE/FACE PROTECTION:
FACE SHIELD AND SAFETY GLASSES USE EQUIPMENT FOR EYE PROTECTION TESTED
AND APPROVED UNDER APPROPRIATE GOVERNMENT STANDARDS SUCH AS NIOSH (US)
OR EN 166(EU).
II. SKIN PROTECTION:
WEAR APPROPRIATE PROTECTIVE EYEGLASSES OR CHEMICAL SAFETY GOGGLES AS
DESCRIBED BY OSHA'S EYE AND FACE PROTECTION REGULATIONS IN 29 CFR
1910.133 OR EUROPEAN STANDARD EN166
III. BODY PROTECTION:
WEAR APPROPRIATE PROTECTIVE CLOTHING. COMPLETE SUIT PROTECTING AGAINST
CHEMICALS, THE TYPE OF PROTECTIVE EQUIPMENT MUST BE SELECTED ACCORDING
TO THE CONCENTRATION AND AMOUNT OF THE DANGEROUS SUBSTANCE AT THE
SPECIFIC WORKPLACE.
IV. RESPIRATORY PROTECTION:
FOLLOW THE OSHA RESPIRATOR REGULATIONS FOUND IN 29 CFR 1910.134 OR
EUROPEAN STANDARD EN 149. USE A NIOSH/MSHA OR EUROPEAN STANDARD EN149
APPROVED RESPIRATOR IF EXPOSURE LIMITS ARE EXCEEDED OR IF IRRITATION
OR OTHER SYMPTOMS ARE EXPERIENCED.
V. CONTROL OF ENVIRONMENTAL EXPOSURE: DO NOT LET PRODUCT ENTER DRAINS
| SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES | |
INFORMATION ON BASIC PHYSICAL AND CHEMICAL PROPERTIES:
APPEARANCE: WHITE TO YELLOW POWDER
ODOR: NO DATA AVAILABLE
ODOR THRESHOLD: NO DATA AVAILABLE
PH: NO DATA AVAILABLE
MELTING / FREEZING POINT: 159 - 163 DEG. C
INITIAL BOILING POINT RANGE: NO DATA AVAILABLE
FLASH POINT: NO DATA AVAILABLE
EVAPORATION RATE: NO DATA AVAILABLE
FLAMMABILITY (SOLID, GAS): NO DATA AVAILABLE
UPPER / LOWER FLAMMABILITY OR EXPLOSIVE LIMITS: NO DATA AVAILABLE
VAPOR PRESSURE: NO DATA AVAILABLE
VAPOR DENSITY: NO DATA AVAILABLE
RELATIVE DENSITY: NO DATA AVAILABLE
WATER SOLUBILITY: NO DATA AVAILABLE
PARTITION COEFFICIENT: NO DATA AVAILABLE
AUTO-IGNITION TEMPERATURE: NO DATA AVAILABLE
DECOMPOSITION TEMPERATURE: NO DATA AVAILABLE
VISCOSITY: NO DATA AVAILABLE
EXPLOSIVE PROPERTIES: NO DATA AVAILABLE
OXIDIZING PROPERTIES: NO DATA AVAILABLE
| SECTION 10 - STABILITY AND REACTIVITY | |
STABILITY: STABLE UNDER RECOMMENDED STORAGE CONDITIONS.
HAZARDOUS DECOMPOSITION PRODUCTS/ HAZARDOUS POLYMERIZATION:
NO DATA AVAILABLE.
INCOMPATIBILITIES: STRONG OXIDIZING AGENT.
| SECTION 11 - TOXICOLOGICAL INFORMATION | |
ACUTE TOXICITY:
LD50 ORAL: 3000 MG/KG (RAT)
LD50 DERMAL: NOT LISTED
LD50 INHALATION: NOT LISTED
CARCINOGENICITY:
COMPONENT CAS# IARC NTP OSHA
METRONIDAZOLE 443-48-1 GROUP 2B REASONABLY ANTICIPATED LISTED
| SECTION 12 - ECOLOGICAL INFORMATION | |
ECOTOXICITY: NO DATA AVAILABLE
PERSISTENCE AND DEGRADABILITY: NO DATA AVAILABLE
BIOACCUMLATIVE POTENTIAL: NO DATA AVAILABLE
MOBILITY IN SOIL: NO DATA AVAILABLE
RESULTS OF PBT AND VPVB ASSESSMENT: NO DATA AVAILABLE
OTHER ADVERSE EFFECTS: NO DATA AVAILABLE
| SECTION 13 - DISPOSAL CONSIDERATIONS | |
WHATEVER CANNOT BE SAVED FOR RECOVERY OR RECYCLING SHOULD BE MANAGED IN
AN APPROPRIATE AND APPROVED WASTE DISPOSAL FACILITY. PROCESSING, USE OR
CONTAMINATION OF THIS PRODUCT MAY CHANGE THE WASTE MANAGEMENT OPTIONS.
STATE AND LOCAL DISPOSAL REGULATIONS MAY DIFFER FROM FEDERAL DISPOSAL
REGULATIONS. DISPOSE OF CONTAINER AND UNUSED CONTENTS IN ACCORDANCE WITH
FEDERAL, STATE AND LOCAL REQUIREMENTS.
| SECTION 14 - TRANSPORT INFORMATION | |
DOT: NOT REGULATED
TDG: NOT REGULATED
IATA: NOT REGULATED
IMDG/IMO: NOT REGULATED
| SECTION 15 - REGULATORY INFORMATION | |
INTERNATIONAL INVENTORIES:
TSCA DSL NDSL ELINCS NLP PICCS ENCS AICS CHINA KECL
LISTED LISTED LISTED LISTED LISTED LISTED
USA FEDERAL REGULATION:
SARA 311/312 HAZARDOUS CATEGORIZATION:
ACUTE HEALTH CHRONIC HEALTH FIRE HAZARD SUDDEN RELEASE REACTIVE
HAZARD HAZARD OF PRESSURE HAZARD
HAZARD
NO YES YES NO NO
TSCA 12(B)/ OSHA/ SARA 313: NOT APPLICABLE
CLEAN WATER ACT/ CLEAN AIR ACT: NOT APPLICABLE
CALIFORNIA PROPOSITION 65: THIS PRODUCT CONTAINS THE FOLLOWING PROPOSITION
65 CHEMICALS:
COMPONENT CAS# CALIFORNIA PROP. 65 CATEGORY
METRONIDAZOLE 443-48-1 CARCINOGEN CARCINOGEN
HMIS RATING:
HEALTH HAZARD 1
CHRONIC HEALTH HAZARD *
FLAMMABILITY 0
PHYSICAL HAZARD 0
NFPA RATING:
HEALTH HAZARD 0
FIRE HAZARD 0
REACTIVITY HAZARD 0
STATE RIGHT TO KNOW:
MASSACHUSETTS NEW JERSEY PENNSYLVANIA ILLINOIS RHODE ISLAND
LISTED LISTED LISTED LISTED LISTED
US DEPARTMENT OF TRANSPORTATION:
REPORTABLE QUANTITY (RQ) DOT MARINE POLLUTANT DOT SEVER MARINE
POLLUTANT
NO NO NO
U.S. DEPARTMENT OF HOMELAND SECURITY:
THIS PRODUCT DOES NOT CONTAIN ANY DHS CHEMICALS.
CANADA:
THIS PRODUCT HAS BEEN CLASSIFIED IN ACCORDANCE WITH THE HAZARD CRITERIA OF
THE CONTROLLED PRODUCTS REGULATIONS (CPR) AND THE SDS CONTAINS ALL THE
INFORMATION REQUIRED BY THE CPR.
THIS SDS COMPLIES WITH THE REQUIREMENTS OF REGULATION (EC)
| SECTION 16 - OTHER INFORMATION | |
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO BE
ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. RESEARCH PRODUCTS
INTERNATIONAL CORP. SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM
HANDLING OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF
INVOICE OR PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE. THIS
PRODUCT IS SOLD FOR LABORATORY RESEARCH AND DEVELOPMENT PURPOSES USE ONLY.