| Common Name: | TETRACYCLINE HCL |
| Manufacturer: | RESEARCH PRODUCTS INTERNATIONAL |
| SDS Revision Date: | 7/6/2018 |
| SDS Format: | No Format Specified |
| Item Number(s): | 30UA78 |
| Manufacturer Model Number(s): |
SDS Table of Contents
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PRODUCT SAFETY DATA SHEET
RESEARCH PRODUCTS INTERNATIONAL
ISSUE DATE: 12/15/14
REV.: 2
REV DATE: 07/06/18
DOCUMENT #: F/RPI/QC 7.7.3-02
PRODUCT NAME: TETRACYCLINE HCl
RPI ITEM NO: T17000
| SECTION 1 - CHEMICAL IDENTIFICATION |  |
PRODUCT NAME: TETRACYCLINE HCl
RPI CATALOG #: T17000
SUPPLIER'S NAME: RESEARCH PRODUCTS INTERNATIONAL CORP.
SUPPLIERS ADDRESS:
410 N BUSINESS CENTER DRIVE MOUNT PROSPECT,
IL 60056
EMERGENCY CONTACT: 1-800-424-9300
OTHER INFORMATION: 847-635-7330
| SECTION 2 - HAZARDS IDENTIFICATION | |
2.1 CLASSIFICATION OF THE SUBSTANCE OR MIXTURE:
GHS CLASSIFICATION IN ACCORDANCE WITH 29 CFR 1910 (OSHA HCS):
H319:
SERIOUS EYE DAMAGE/EYE IRRITATION: CATEGORY 2A
H361:
REPRODUCTIVE TOXICITY: CATEGORY 2
H411:
HAZARDOUS TO THE AQUATIC ENVIRONMENT, LONG TERM HAZARD: CATEGORY 2
2.2 GHS LABEL ELEMENTS, INCLUDING HAZARD AND PRECAUTIONARY STATEMENT(S):
PICTOGRAM:
HEALTH HAZARD
EXCLAMATION MARK
ENVIRONMENT
SIGNAL WORD: WARNING
HAZARD STATEMENT(S):
H319: CAUSE SERIOUS EYE IRRITATION
H361: SUSPECTED OF DAMAGING FERTILITY OR THE UNBORN CHILD
H411: TOXIC TO AQUATIC LIFE WITH LONG LASTING EFFECTS
PREVENTION, RESPONSE, STORAGE AND DISPOSAL PRECAUTIONARY STATEMENT(S):
P201: OBTAIN SPECIAL INSTRUCTIONS BEFORE USE.
P202:
DO NOT HANDLE UNTIL ALL SAFETY PRECAUTIONS HAVE BEEN READ AND UNDERSTOOD.
P264: WASH SKIN THOROUGHLY AFTER HANDLING
P273: AVOID RELEASE TO THE ENVIRONMENT
P280:
WEAR PROTECTIVE GLOVES/PROTECTIVE CLOTHING/EYE PROTECTION/FACE
PROTECTION.
P305 + P351 + P338:
IF IN EYES:
RINSE CAUTIOUSLY WITH WATER FOR SEVERAL MINUTES. REMOVE CONTACT LENSES,
IF PRESENT AND EASY TO DO. CONTINUE RINSING.
P308 + P313:
IF EXPOSED OR CONCERNED: GET MEDICAL ADVICE/ ATTENTION.
P337+P313:
IF EYE IRRITATION PERSISTS: GET MEDICAL ADVICE/ATTENTION.
P405: STORE LOCKED UP.
P391: COLLECT SPILLAGE.
P501: DISPOSE OF CONTENTS/ CONTAINER TO AN APPROVED WASTE DISPOSAL PLANT.
| SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS | |
CAS NUMBER: 64-75-5
EINECS NUMBER: 200-593-8
FORMULA: C22H24N2O8 x HCl
MOLECULAR WEIGHT: 480.90 G/MOL
| SECTION 4 - FIRST-AID MEASURES | |
4.1 DESCRIPTION OF FIRST AID MEASURES:
GENERAL ADVICE: CONSULT A DOCTOR AND SHOW THIS SAFETY DATA SHEET.
I. IF INHALED:
REMOVE TO FRESH AIR AND MONITOR BREATHING. IF BREATHING BECOMES DIFFICULT,
GIVE OXYGEN. IF BREATHING STOPS, GIVE ARTIFICIAL RESPIRATION. CONSULT A
DOCTOR.
II. IN CASE OF SKIN CONTACT:
IMMEDIATELY WASH SKIN WITH COPIOUS AMOUNTS OF SOAP AND WATER FOR AT LEAST
15 MINUTES. REMOVE CONTAMINATED CLOTHING AND SHOES AND WASH BEFORE REUSE.
CONSULT A DOCTOR.
III. IN CASE OF EYE CONTACT:
FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. CONSULT
A DOCTOR.
IV. IF SWALLOWED:
RINSE MOUTH WITH WATER. DO NOT INDUCE VOMITING UNLESS DIRECTED TO DO SO
BY MEDICAL PERSONNEL. NEVER GIVE ANYTHING BY MOUTH TO AN UNCONSCIOUS
PERSON. CONSULT A DOCTOR.
4.2 MOST IMPORTANT SYMPTOMS AND EFFECTS, BOTH ACUTE AND DELAYED:
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL AND TOXICOLOGICAL
PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
4.3 INDICATION OF IMMEDIATE MEDICAL ATTENTION AND SPECIAL TREATMENT NEEDED:
SHOW THIS SAFETY DATA SHEET TO THE DOCTOR IN ATTENDANCE. IMMEDIATE MEDICAL
ATTENTION IS REQUIRED.
| SECTION 5 - FIRE FIGHTING MEASURES | |
5.1 EXTINGUISHING MEDIA:
SUITABLE EXTINGUISHING MEDIA:
USE WATER SPRAY, ALCOHOL-RESISTANT FOAM, DRY CHEMICAL OR CARBON DIOXIDE
5.2 SPECIAL HAZARDS ARISING FROM THE SUBSTANCE OR MIXTURE:
NO DATA AVAILABLE
5.3 PRECAUTIONS FOR FIRE-FIGHTERS:
WEAR SUITABLE PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES
AND SELF-CONTAINED BREATHING APPARATUS.
5.4 FURTHER INFORMATION: NO DATA AVAILABLE
| SECTION 6 - ACCIDENTAL RELEASE MEASURES | |
6.1 PERSONAL PRECAUTIONS, PROTECTIVE EQUIPMENT AND EMERGENCY PROCEDURES:
DO NOT TAKE ACTION WITHOUT SUITABLE PROTECTIVE CLOTHING - SEE SECTION 8
OF SDS. EVACUATE PERSONNEL TO SAFE AREAS. ENSURE ADEQUATE VENTILATION.
AVOID BREATHING VAPORS, MIST, DUST OR GAS.
6.2 ENVIRONMENTAL PRECAUTIONS: DO NOT LET PRODUCT ENTER DRAINS.
6.3 METHODS AND MATERIALS FOR CONTAINMENT AND CLEANING UP:
COVER SPILLAGE WITH SUITABLE ABSORBENT MATERIAL. USING NON-SPARK TOOLS,
SWEEP UP MATERIAL AND PLACE IN AN APPROPRIATE CONTAINER. DECONTAMINATE
SPILL SITE WITH 10% CAUSTIC SOLUTION AND VENTILATE AREA UNTIL AFTER
DISPOSAL IS COMPLETE. HOLD ALL MATERIAL FOR APPROPRIATE DISPOSAL AS
DESCRIBED UNDER SECTION 13 OF SDS.
6.4 REFERENCE TO OTHER SECTIONS:
FOR REQUIRED PPE SEE SECTION 8. FOR DISPOSAL SEE SECTION 13.
| SECTION 7 - HANDLING AND STORAGE | |
7.1 PRECAUTIONS FOR SAFE HANDLING:
AVOID CONTACT WITH SKIN AND EYES. AVOID FORMATION OF DUST AND AEROSOLS.
FURTHER PROCESSING OF SOLID MATERIALS MAY RESULT IN THE FORMATION OF
COMBUSTIBLE DUSTS. THE POTENTIAL FOR COMBUSTIBLE DUST FORMATION SHOULD
BE TAKEN INTO CONSIDERATION BEFORE ADDITIONAL PROCESSING OCCURS. PROVIDE
APPROPRIATE EXHAUST VENTILATION AT PLACES WHERE DUST IS FORMED. FOR
PRECAUTIONS SEE SECTION 2.
7.2 CONDITIONS FOR SAFE STORAGE, INCLUDING ANY INCOMPATIBILITIES:
STORE IN COOL, WELL-VENTILATED AREA. KEEP AWAY FROM DIRECT SUNLIGHT.
KEEP CONTAINER TIGHTLY SEALED UNTIL READY FOR USE. STORE AT ROOM
TEMPERATURE.
7.3 SPECIFIC END USE(S):
APART FROM THE USES MENTIONED IN SECTION 1 NO OTHER SPECIFIC USES
ARE STIPULATED.
| SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION | |
8.1 CONTROL PARAMETERS:
COMPONENTS WITH WORKPLACE CONTROL PARAMETERS:
CONTAINS NO SUBSTANCES WITH OCCUPATIONAL EXPOSURE LIMIT VALUES.
8.2 EXPOSURE CONTROLS:
I. APPROPRIATE ENGINEERING CONTROLS:
HANDLE IN ACCORDANCE WITH GOOD INDUSTRIAL HYGIENE AND SAFETY PRACTICE.
WASH HANDS BEFORE BREAKS AND AT THE END OF WORKDAY.
8.3 PERSONAL PROTECTIVE EQUIPMENT:
I. EYE/FACE PROTECTION:
FACE SHIELD AND SAFETY GLASSES USE EQUIPMENT FOR EYE PROTECTION TESTED AND
APPROVED UNDER APPROPRIATE GOVERNMENT STANDARDS SUCH AS NIOSH (US) OR EN
166(EU).
II. SKIN PROTECTION:
WEAR APPROPRIATE PROTECTIVE EYEGLASSES OR CHEMICAL SAFETY GOGGLES AS
DESCRIBED BY OSHA'S EYE AND FACE PROTECTION REGULATIONS IN 29 CFR
1910.133 OR EUROPEAN STANDARD EN166
III. BODY PROTECTION:
WEAR APPROPRIATE PROTECTIVE CLOTHING. COMPLETE SUIT PROTECTING AGAINST
CHEMICALS, THE TYPE OF PROTECTIVE EQUIPMENT MUST BE SELECTED ACCORDING
TO THE CONCENTRATION AND AMOUNT OF THE DANGEROUS SUBSTANCE AT THE
SPECIFIC WORKPLACE.
IV. RESPIRATORY PROTECTION:
FOLLOW THE OSHA RESPIRATOR REGULATIONS FOUND IN 29 CFR 1910.134 OR
EUROPEAN STANDARD EN 149. USE A NIOSH/MSHA OR EUROPEAN STANDARD EN149
APPROVED RESPIRATOR IF EXPOSURE LIMITS ARE EXCEEDED OR IF IRRITATION
OR OTHER SYMPTOMS ARE EXPERIENCED.
V. CONTROL OF ENVIRONMENTAL EXPOSURE: DO NOT LET PRODUCT ENTER DRAINS
| SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES | |
INFORMATION ON BASIC PHYSICAL AND CHEMICAL PROPERTIES:
APPEARANCE: POWDER
ODOR: NO DATA AVAILABLE
ODOR THRESHOLD: NO DATA AVAILABLE
PH: NO DATA AVAILABLE
MELTING / FREEZING POINT: 220 - 223 DEG. C
INITIAL BOILING POINT RANGE: NO DATA AVAILABLE
FLASH POINT: NO DATA AVAILABLE
EVAPORATION RATE: NO DATA AVAILABLE
FLAMMABILITY (SOLID, GAS): NO DATA AVAILABLE
UPPER / LOWER FLAMMABILITY OR EXPLOSIVE LIMITS: NO DATA AVAILABLE
VAPOR PRESSURE: NO DATA AVAILABLE
VAPOR DENSITY: NO DATA AVAILABLE
RELATIVE DENSITY: NO DATA AVAILABLE
WATER SOLUBILITY: NO DATA AVAILABLE
PARTITION COEFFICIENT: NO DATA AVAILABLE
AUTO-IGNITION TEMPERATURE: NO DATA AVAILABLE
DECOMPOSITION TEMPERATURE: NO DATA AVAILABLE
VISCOSITY: NO DATA AVAILABLE
EXPLOSIVE PROPERTIES: NO DATA AVAILABLE
OXIDIZING PROPERTIES: NO DATA AVAILABLE
| SECTION 10 - STABILITY AND REACTIVITY | |
STABILITY: STABLE UNDER RECOMMENDED STORAGE CONDITIONS.
HAZARDOUS DECOMPOSITION PRODUCTS:
HAZARDOUS DECOMPOSITION PRODUCTS FORMED UNDER FIRE CONDITIONS. - CARBON
OXIDES, NITROGEN OXIDES (NOX), HYDROGEN CHLORIDE GAS.
HAZARDOUS POLYMERIZATION: NO DATA AVAILABLE.
INCOMPATIBILITIES: STRONG OXIDIZING AGENTS.
| SECTION 11 - TOXICOLOGICAL INFORMATION | |
ACUTE TOXICITY:
LD50 ORAL: 6443 MG/KG (RAT)
LD50 DERMAL: NOT LISTED
LD50 INHALATION: NOT LISTED
| SECTION 12 - ECOLOGICAL INFORMATION | |
ECOTOXICITY/PERSISTENCE AND DEGRADABILITY: NO DATA AVAILABLE
BIOACCUMLATIVE POTENTIAL/MOBILITY IN SOIL: NO DATA AVAILABLE
RESULTS OF PBT AND VPVB ASSESSMENT: NO DATA AVAILABLE
OTHER ADVERSE EFFECTS: NO DATA AVAILABLE
CHRONIC TOXICITY:
THERE ARE NO KNOWN CARCINOGENIC CHEMICALS IN THIS PRODUCT
| SECTION 13 - DISPOSAL CONSIDERATIONS | |
WHATEVER CANNOT BE SAVED FOR RECOVERY OR RECYCLING SHOULD BE MANAGED IN AN
APPROPRIATE AND APPROVED WASTE DISPOSAL FACILITY. PROCESSING, USE OR
CONTAMINATION OF THIS PRODUCT MAY CHANGE THE WASTE MANAGEMENT OPTIONS.
STATE AND LOCAL DISPOSAL REGULATIONS MAY DIFFER FROM FEDERAL DISPOSAL
REGULATIONS. DISPOSE OF CONTAINER AND UNUSED CONTENTS IN ACCORDANCE WITH
FEDERAL, STATE AND LOCAL REQUIREMENTS.
| SECTION 14 - TRANSPORT INFORMATION | |
UN# PROPER SHIPPING NAME HAZARD CLASS PACKAGING GROUP
DOT NOT DANGEROUS GOODS
IATA 3077 ENVIRONMENTALLY HAZARDOUS 9 III
SUBSTANCE, SOLID, N.O.S.
(TETRACYCLINE
HYDROCHLORIDE)
IMDG/IMO 3077 ENVIRONMENTALLY HAZARDOUS 9 III
SUBSTANCE, SOLID, N.O.S.
(TETRACYCLINE
HYDROCHLORIDE) MARINE
POLLUTANT: YES
FURTHER INFORMATION:
EHS-MARK REQUIRED (ADR 2.2.9.1.10, IMDG CODE 2.10.3) FOR SINGLE PACKAGING'S
AND COMBINATION PACKAGING'S CONTAINING INNER PACKAGING'S WITH DANGEROUS
GOODS > 5L FOR LIQUIDS OR > 5KG FOR SOLIDS
| SECTION 15 - REGULATORY INFORMATION | |
INTERNATIONAL INVENTORIES:
TSCA DSL NDSL ELINCS NLP PICCS ENCS AICS CHINA KECL
LISTED LISTED LISTED LISTED LISTED LISTED
USA FEDERAL REGULATION:
SARA 311/312 HAZARDOUS CATEGORIZATION:
ACUTE HEALTH CHRONIC HEALTH FIRE HAZARD SUDDEN RELEASE REACTIVE
HAZARD HAZARD OF PRESSURE HAZARD
HAZARD
YES YES NO NO NO
CLEAN WATER ACT/ CLEAN AIR ACT/OSHA/TSCA 12(B): NOT APPLICABLE
SARA 313:
SECTION 313 OF TITLE III OF THE SUPERFUND AMENDMENTS AND REAUTHORIZATION
ACT OF 1986 (SARA). THIS PRODUCT CONTAINS A CHEMICAL OR CHEMICALS WHICH
ARE SUBJECT TO THE REPORTING REQUIREMENTS OF THE ACT AND TITLE 40 OF THE
CODE OF FEDERAL REGULATIONS, PART 372
COMPONENT CAS# WEIGHT % SARA 313 - THRESHOLD VALUES %
TETRACYCLINE 64-75-5 95.0-100.0 1.0
HYDROCHLORIDE
CALIFORNIA PROPOSITION 65:
THIS PRODUCT CONTAINS THE FOLLOWING PROPOSITION 65 CHEMICALS
COMPONENT CAS# CALIFORNIA PROP. 65
TETRACYCLINE HYDROCHLORIDE 64-75-5 DEVELOPMENTAL
HMIS RATING:
HEALTH HAZARD 2
CHRONIC HEALTH HAZARD *
FLAMMABILITY 0
PHYSICAL HAZARD 0
NFPA RATING:
HEALTH HAZARD 2
FIRE HAZARD 0
REACTIVITY HAZARD 1
STATE RIGHT TO KNOW:
MASSACHUSETTS NEW JERSEY PENNSYLVANIA ILLINOIS RHODE ISLAND
LISTED LISTED
US DEPARTMENT OF TRANSPORTATION:
REPORTABLE QUANTITY (RQ) DOT MARINE POLLUTANT DOT SEVER MARINE
POLLUTANT
NO NO NO
U.S. DEPARTMENT OF HOMELAND SECURITY:
THIS PRODUCT DOES NOT CONTAIN ANY DHS CHEMICALS.
CANADA:
THIS PRODUCT HAS BEEN CLASSIFIED IN ACCORDANCE WITH THE HAZARD CRITERIA OF
THE CONTROLLED PRODUCTS REGULATIONS (CPR) AND THE SDS CONTAINS ALL THE
INFORMATION REQUIRED BY THE CPR.
THIS SDS COMPLIES WITH THE REQUIREMENTS OF REGULATION (EC).
| SECTION 16 - OTHER INFORMATION | |
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO BE
ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. RESEARCH PRODUCTS
INTERNATIONAL CORP. SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM
HANDLING OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF
INVOICE OR PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE. THIS
PRODUCT IS SOLD FOR LABORATORY RESEARCH AND DEVELOPMENT PURPOSES USE ONLY.