| Common Name: | ETHYLENE GLYCOL, PURIFIED |
| Manufacturer: | SPECTRUM CHEMICALS & LABORATORY PRODUCTS |
| SDS Revision Date: | 11/19/2019 |
| SDS Format: | GHS-US |
| Item Number(s): | 39H285, 39H287 |
| Manufacturer Model Number(s): |
SDS Table of Contents
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SPECTRUM(R*)
SAFETY DATA SHEET
S
ISO 9001-2015 REGISTERED
PREPARATION DATE: 3/20/2015
REVISION DATE: 11/19/2019
REVISION NUMBER: G2
| 1. IDENTIFICATION |  |
PRODUCT IDENTIFIER:
PRODUCT CODE: E1052
PRODUCT NAME: ETHYLENE GLYCOL, PURIFIED
OTHER MEANS OF IDENTIFICATION:
SYNONYMS:
1,2-DIHYDROXYETHANE
1,2-ETHANDIOL
1,2-ETHANEDIOL
ETHANE-1,2-DIOL
ETHYLENE ALCOHOL
ETHYLENE DIHYDRATE
GLYCOL ALCOHOL
M.E.G.
MONOETHYLENE GLYCOL
NORKOOL
TESCOL
CAS #: 107-21-1
RTECS #: KW2975000
CI#: NOT AVAILABLE
RECOMMENDED USE OF THE CHEMICAL AND RESTRICTIONS ON USE:
RECOMMENDED USE:
SOLVENT. ANTIFREEZE IN COOLING AND HEATING SYSTEMS. IN HYDRAULIC BRAKE
FLUIDS AND DEICING SOLUTIONS. HEAT-TRANSFER AGENT.
USES ADVISED AGAINST: NO INFORMATION AVAILABLE
SUPPLIER:
SPECTRUM CHEMICAL MFG. CORP
14422 SOUTH SAN PEDRO ST.
GARDENA, CA 90248
(310) 516-8000
ORDER ONLINE AT: HTTPS://WWW.SPECTRUMCHEMICAL.COM
EMERGENCY TELEPHONE NUMBER:
CHEMTREC: 1-800-424-9300
CONTACT PERSON: TOM TYNER (USA - WEST COAST)
CONTACT PERSON: IBAD TIRMIZ (USA - EAST COAST)
| 2. HAZARDS IDENTIFICATION | |
CLASSIFICATION:
THIS CHEMICAL IS CONSIDERED HAZARDOUS BY THE 2012 OSHA HAZARD COMMUNICATION
STANDARD (29 CFR 1910.1200)
CONSIDERED A DANGEROUS SUBSTANCE OR MIXTURE ACCORDING TO THE GLOBALLY
HARMONIZED SYSTEM (GHS)
ACUTE TOXICITY - ORAL: CATEGORY 4
SERIOUS EYE DAMAGE/EYE IRRITATION: CATEGORY 2
SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE): CATEGORY 1
SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE): CATEGORY 1
LABEL ELEMENTS:
DANGER:
HAZARD STATEMENTS:
HARMFUL IF SWALLOWED
CAUSES SERIOUS EYE IRRITATION
CAUSES DAMAGE TO ORGANS
CAUSES DAMAGE TO ORGANS THROUGH PROLONGED OR REPEATED EXPOSURE
EXCLAMATION MARK
HEALTH HAZARD
HAZARDS NOT OTHERWISE CLASSIFIED (HNOC): NOT APPLICABLE
OTHER HAZARDS: CAUSES MILD SKIN IRRITATION
PRECAUTIONARY STATEMENTS - PREVENTION:
WASH FACE, HANDS AND ANY EXPOSED SKIN THOROUGHLY AFTER HANDLING
DO NOT EAT, DRINK OR SMOKE WHEN USING THIS PRODUCT
WEAR EYE/FACE PROTECTION
DO NOT BREATHE MIST OR VAPORS
PRECAUTIONARY STATEMENTS - RESPONSE:
IF IN EYES:
RINSE CAUTIOUSLY WITH WATER FOR SEVERAL MINUTES. REMOVE CONTACT LENSES,
IF PRESENT AND EASY TO DO. CONTINUE RINSING.
IF EYE IRRITATION PERSISTS: GET MEDICAL ATTENTION.
IF SWALLOWED:
CALL A POISON CENTER OR PHYSICIAN IF YOU FEEL UNWELL RINSE MOUTH
PRECAUTIONARY STATEMENTS - STORAGE: STORE LOCKED UP
PRECAUTIONARY STATEMENTS - DISPOSAL:
DISPOSE OF CONTENTS AND CONTAINER TO AN APPROVED WASTE DISPOSAL PLANT IN
ACCORDANCE WITH LOCAL, REGIONAL, NATIONAL AND INTERNATIONAL REGULATIONS
AS APPLICABLE
| 3. COMPOSITION/INFORMATION ON INGREDIENTS | |
COMPONENT CAS NO WEIGHT-%
ETHYLENE GLYCOL 107-21-1 100
| 4. FIRST AID MEASURES | |
FIRST AID MEASURES:
GENERAL ADVICE:
NATIONAL CAPITAL POISON CENTER IN THE UNITED STATES CAN PROVIDE ASSISTANCE
IF YOU HAVE A POISON EMERGENCY AND NEED TO TALK TO A POISON SPECIALIST.
CALL 1-800-222-1222.
SKIN CONTACT:
WASH OFF IMMEDIATELY WITH SOAP AND PLENTY OF WATER REMOVING ALL
CONTAMINATED CLOTHING AND SHOES. GET MEDICAL ATTENTION IF IRRITATION
DEVELOPS.
EYE CONTACT: FLUSH EYES WITH WATER FOR 15 MINUTES. GET MEDICAL ATTENTION.
INHALATION:
MOVE TO FRESH AIR. IF NOT BREATHING, GIVE ARTIFICIAL RESPIRATION. IF
BREATHING IS DIFFICULT, GIVE OXYGEN. GET MEDICAL ATTENTION.
INGESTION:
DO NOT INDUCE VOMITING WITHOUT MEDICAL ADVICE. NEVER GIVE ANYTHING BY MOUTH
TO AN UNCONSCIOUS PERSON. OBTAIN MEDICAL ATTENTION.
MOST IMPORTANT SYMPTOMS AND EFFECTS, BOTH ACUTE AND DELAYED:
SYMPTOMS:
CAUSES EYE IRRITATION
MILD SKIN IRRITATION
CENTRAL NERVOUS SYSTEM EFFECTS
INGESTION MAY CAUSE NAUSEA, VOMITING, AND DIARRHEA
MAY CAUSE METABOLIC ACIDOSIS
IT MAY AFFECT THE KIDNEYS
MAY AFFECT THE LIVER
MAY AFFECT THE BLOOD
MAY CAUSE HYPOCALCEMIA
MAY AFFECT THE CARDIOVASCULAR SYSTEM
MAY AFFECT THE BONE MARROW
INDICATION OF ANY IMMEDIATE MEDICAL ATTENTION AND SPECIAL TREATMENT NEEDED:
NOTES TO PHYSICIAN:
SUPPORT VITAL FUNCTIONS. CORRECT FOR DEHYDRATION AND SHOCK. MANAGE FLUID
BALANCE. CORRECT METABOLIC ACIDOSIS WITH INTRAVENOUS ADMINISTRATION OF
SODIUM BICARBONATE, ADJUSTING THE ADMINISTRATION RATE ACCORDING TO REPEATED
AND FREQUENT MEASUREMENT OF THE ACID/BASE STATUS. THE CURRENTLY RECOMMENDED
MEDICAL MANAGEMENT OF ETHYLENE GLYCOL POISONING INCLUDES THE ELIMINATION
OF ETHYLENE GLYCOL AND METABOLITES. THIS MAY BE ACHIEVED BY THE FOLLOWING
METHODS:
1. EMPTYING THE STOMACH BY GASTRIC LAVAGE. IT IS USEFUL IF INITIATED LESS
THAN 1 HOUR AFTER INGESTION.
2. ADMINISTER ETHANOL (ORALLY OR INTRAVENOUSLY) OR FOMEPIZOLE
(4-METHYLPYRAZOLE OR ANITZOL) THERAPY (INTRAVENOUSLY) AS AN ANTIDOTE TO
INHIBIT THE FORMATION OF TOXIC METABOLITES. HEMODIALYSIS MAYBE AVOIDED IF
PATIENTS ARE DIAGNOSED AND TREATED EARLY WITH THE ABOVE METHODS, AND
ETHANOL OR FOMEPIZOLE THERAPY IS EFFECTIVE, AND METABOLIC ACIDOSIS HAS BEEN
CORRECTED. HOWEVER, ONCE SEVERE ACIDOSIS AND RENAL FAILURE HAVE OCCURED,
HEMODIALYIS IS NECESSARY TO EFFECTIVELY REMOVE ETHYLENE GLYCOL AND TOXIC
METABOLITES AND CORRECTING METABOLIC ACIDOSIS.
PROTECTION OF FIRST-AIDERS:
FIRST-AID PROVIDERS:
AVOID EXPOSURE TO BLOOD OR BODY FLUIDS. WEAR GLOVES AND OTHER NECESSARY
PROTECTIVE CLOTHING. DISPOSE OF CONTAMINATED CLOTHING AND EQUIPMENT AS
BIO-HAZARDOUS WASTE.
| 5. FIRE-FIGHTING MEASURES | |
EXTINGUISHING MEDIA:
SUITABLE EXTINGUISHING MEDIA:
CARBON DIOXIDE (CO2). DRY CHEMICAL. WATER SPRAY MIST OR FOAM.
UNSUITABLE EXTINGUISHING MEDIA: NO INFORMATION AVAILABLE.
SPECIFIC HAZARDS ARISING FROM THE CHEMICAL:
HAZARDOUS COMBUSTION PRODUCTS: CARBON MONOXIDE, CARBON DIOXIDE.
SPECIFIC HAZARDS:
MAY BE COMBUSTIBLE AT HIGH TEMPERATURES. MAY BE IGNITED BY HEAT, SPARKS
OR FLAMES. CONTAINER EXPLOSION MAY OCCUR UNDER FIRE CONDITIONS OR WHEN
HEATED.
SPECIAL PROTECTIVE ACTIONS FOR FIREFIGHTERS:
SPECIFIC METHODS: NO INFORMATION AVAILABLE
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS:
AS IN ANY FIRE, WEAR SELF-CONTAINED BREATHING APPARATUS PRESSURE-DEMAND,
MSHA/NIOSH (APPROVED OR EQUIVALENT) AND FULL PROTECTIVE GEAR
| 6. ACCIDENTAL RELEASE MEASURES | |
PERSONAL PRECAUTIONS, PROTECTIVE EQUIPMENT AND EMERGENCY PROCEDURES:
PERSONAL PRECAUTIONS:
ENSURE ADEQUATE VENTILATION. USE PERSONAL PROTECTIVE EQUIPMENT. AVOID
CONTACT WITH SKIN, EYES AND CLOTHING. REMOVE ALL SOURCES OF IGNITION.
ENVIRONMENTAL PRECAUTIONS:
PREVENT FURTHER LEAKAGE OR SPILLAGE IF SAFE TO DO SO. PREVENT ENTRY INTO
WATERWAYS, SEWERS, BASEMENTS OR CONFINED AREAS. IN CASE OF LARGE SPILL,
DIKE IF NEEDED. DIKE FAR AHEAD OF LIQUID SPILL FOR LATER DISPOSAL.
METHODS AND MATERIAL FOR CONTAINMENT AND CLEANING UP:
METHODS FOR CONTAINMENT:
STOP LEAK IF YOU CAN DO IT WITHOUT RISK. ABSORB SPILL WITH INERT MATERIAL
(E.G. VERMICULITE, DRY SAND OR EARTH).
METHODS FOR CLEANING UP:
USE APPROPRIATE TOOLS TO PUT THE SPILLED MATERIAL IN A SUITABLE CHEMICAL
WASTE DISPOSAL CONTAINER. CLEAN CONTAMINATED SURFACE THOROUGHLY.
| 7. HANDLING AND STORAGE | |
PRECAUTIONS FOR SAFE HANDLING:
TECHNICAL MEASURES/PRECAUTIONS:
PROVIDE SUFFICIENT AIR EXCHANGE AND/OR EXHAUST IN WORK ROOMS. KEEP AWAY
FROM INCOMPATIBLE MATERIALS.
SAFE HANDLING ADVICE:
WEAR PERSONAL PROTECTIVE EQUIPMENT. AVOID CONTACT WITH SKIN, EYES AND
CLOTHING. DO NOT INGEST. DO NOT BREATHE VAPORS OR SPRAY MIST. KEEP AWAY
FROM HEAT AND SOURCES OF IGNITION. HANDLE IN ACCORDANCE WITH GOOD
INDUSTRIAL HYGIENE AND SAFETY PRACTICE.
CONDITIONS FOR SAFE STORAGE, INCLUDING ANY INCOMPATIBILITIES:
TECHNICAL MEASURES/STORAGE CONDITIONS:
HYGROSCOPIC. KEEP CONTAINER TIGHTLY CLOSED IN A DRY AND WELL-VENTILATED
PLACE. STORE AT ROOM TEMPERATURE IN THE ORIGINAL CONTAINER. STORE AWAY
FROM INCOMPATIBLE MATERIALS.
INCOMPATIBLE MATERIALS:
OXIDIZING AGENTS
ACIDS
CHLOROSULFONIC ACID
OLEUM
ISOCYANATES
ALIPHATIC AMINES
HYDROXYL COMPOUNDS
| 8. EXPOSURE CONTROLS/PERSONAL PROTECTION | |
CONTROL PARAMETERS:
NATIONAL OCCUPATIONAL EXPOSURE LIMITS:
UNITED STATES:
COMPONENT CAS NO OSHA NIOSH ACGIH AIHA WEEL
ETHYLENE GLYCOL 107-21-1 NONE NONE 50 PPM STEL NONE
VAPOR FRACTION
10 MG/M3 STEL
INHALABLE
PARTICULATE
MATTER, AEROSOL
ONLY
25 PPM TWA
VAPOR FRACTION
CANADA:
COMPONENT CAS NO
ETHYLENE GLYCOL 107-21-1
COMPONENT CANADA - CANADA - CANADA - CANADA -
ALBERTA BRITISH ONTARIO QUEBEC
COLUMBIA
ETHYLENE GLYCOL 100 MG/M3 10 MG/M3 TWA 100 MG/M3 50 PPM
CEILING PARTICULATE CEILING CEILING
AEROSOL ONLY
20 MG/M3 STEL 127 MG/M3
PARTICULATE CEILING
100 MG/M3
CEILING
AEROSOL
50 PPM CEILING
VAPOUR
AUSTRALIA AND MEXICO:
COMPONENT CAS NO AUSTRALIA MEXICO
ETHYLENE GLYCOL 107-21-1 40 PPM STEL 100 MG/M3 CEILING
104 MG/M3 STEL
10 MG/M3 TWA
20 PPM TWA
52 MG/M3 TWA
APPROPRIATE ENGINEERING CONTROLS:
ENGINEERING MEASURES TO REDUCE EXPOSURE:
ENSURE ADEQUATE VENTILATION. PROVIDE EXHAUST VENTILATION OR OTHER
ENGINEERING CONTROLS TO KEEP THE AIRBORNE CONCENTRATIONS OF VAPORS
AND MIST BELOW THEIR RESPECTIVE THRESHOLD LIMIT VALUE.
INDIVIDUAL PROTECTION MEASURES, SUCH AS PERSONAL PROTECTIVE EQUIPMENT:
PERSONAL PROTECTIVE EQUIPMENT:
EYE PROTECTION: GOGGLES
SKIN AND BODY PROTECTION:
LONG SLEEVED CLOTHING
CHEMICAL RESISTANT APRON
GLOVES
RESPIRATORY PROTECTION:
RESPIRATORY PROTECTION IS NOT NECESSARY FOR NORMAL HANDLING. GOOD ROOM
VENTILATION OR USE OF LOCAL EXHAUST (FUME HOOD) IS SUFFICIENT. USE A VAPOR
RESPIRATOR UNDER CONDITIONS WHERE EXPOSURE TO THE SUBSTANCE IS APPARENT
(E.G. GENERATION OF HIGH CONCENTRATIONS OF MIST OR VAPOR, INADEQUATE
VENTILATION, DEVELOPMENT OF RESPIRATORY TRACT IRRITATION), AND ENGINEERING
CONTROLS ARE NOT FEASIBLE. BE SURE TO USE AN APPROVED/CERTIFIED RESPIRATOR
OR EQUIVALENT.
HYGIENE MEASURES:
AVOID CONTACT WITH SKIN, EYES AND CLOTHING. WASH HANDS BEFORE BREAKS AND
IMMEDIATELY AFTER HANDLING THE PRODUCT WHEN USING, DO NOT EAT, DRINK OR
SMOKE.
| 9. PHYSICAL AND CHEMICAL PROPERTIES | |
PHYSICAL STATE: LIQUID
APPEARANCE: SYRUPY.
COLOR: CLEAR. COLORLESS.
ODOR: NONE.
TASTE: SWEET.
FORMULA: C2-H6-O2
MOLECULAR/FORMULA WEIGHT (G/MOLE): 62.07
FLAMMABILITY (SOLID, GAS): NO DATA AVAILABLE
FLASHPOINT (DEG. C/ DEG. F): 111-119 DEG. C/231.8-246.2 DEG. F
FLASH POINT TESTED ACCORDING TO: CLOSED CUP
AUTOIGNITION TEMPERATURE (DEG. C/DEG. F): 398-413 DEG. C/748.4-770 DEG. F
LOWER EXPLOSION LIMIT (%): 3.2%
UPPER EXPLOSION LIMIT (%): 15.3%
MELTING POINT/RANGE(DEG. C/DEG. F): -13 TO -11 DEG. C/8.6-12.2 DEG. F
DECOMPOSITION TEMPERATURE(DEG. C/DEG. F): NO INFORMATION AVAILABLE
BOILING POINT/RANGE (DEG. C/DEG. F): 196-199 DEG. C/384.8-390.2 DEG. F
BULK DENSITY: NO INFORMATION AVAILABLE
DENSITY (G/CM3): 1.1088-1.115 @ 20 DEG. C
SPECIFIC GRAVITY: 1.1151-1.1156 @ 20 DEG. C
PH: NO INFORMATION AVAILABLE
VAPOR PRESSURE @ 20 DEG. C (KPA): 0.008 TO 0.01
EVAPORATION RATE: NO INFORMATION AVAILABLE
VAPOR DENSITY: 2.14
VOC CONTENT (G/L): NO INFORMATION AVAILABLE
ODOR THRESHOLD (PPM): NO INFORMATION AVAILABLE
PARTITION COEFFICIENT (N-OCTANOL/WATER): -1.36 TO -1.93
VISCOSITY: NO INFORMATION AVAILABLE
MISCIBILITY:
MISCIBLE WITH WATER
MISCIBLE WITH GLACIAL ACETIC ACID
MISCIBLE WITH ACETONE
MISCIBLE WITH ALDEHYDES
MISCIBLE WITH LOWER ALIPHATIC ALCOHOLS
MISCIBLE WITH GLYCEROL
MISCIBLE WITH PYRIDINE
SOLUBILITY:
SLIGHTLY SOLUBLE IN ETHER
PRACTICALLY INSOLUBLE IN PETROLEUM ETHER
PRACTICALLY INSOLUBLE IN BENZENE
| 10. STABILITY AND REACTIVITY | |
REACTIVITY:
REACTIVE WITH OXIDIZING AGENTS
REACTIVE WITH ACIDS
CHEMICAL STABILITY:
STABILITY: STABLE UNDER RECOMMENDED STORAGE CONDITIONS.
POSSIBILITY OF HAZARDOUS REACTIONS: HAZARDOUS POLYMERIZATION DOES NOT OCCUR
CONDITIONS TO AVOID:
HEAT. IGNITION SOURCES. EXPOSURE TO MOIST AIR. EXPOSURE TO MOISTURE.
INCOMPATIBLE MATERIALS.
INCOMPATIBLE MATERIALS:
OXIDIZING AGENTS
ACIDS
CHLOROSULFONIC ACID
OLEUM
ISOCYANATES
ALIPHATIC AMINES
HYDROXYL COMPOUNDS
HAZARDOUS DECOMPOSITION PRODUCTS: CARBON MONOXIDE. CARBON DIOXIDE.
OTHER INFORMATION:
CORROSIVITY: NO INFORMATION AVAILABLE
SPECIAL REMARKS ON CORROSIVITY: NO INFORMATION AVAILABLE
| 11. TOXICOLOGICAL INFORMATION | |
INFORMATION ON LIKELY ROUTES OF EXPOSURE:
PRINCIPAL ROUTES OF EXPOSURE: SKIN. EYES. INGESTION. RESPIRATORY SYSTEM.
ACUTE TOXICITY:
COMPONENT INFORMATION:
ETHYLENE GLYCOL:
CAS NO: 107-21-1
LD50/ORAL/RAT: 4700 MG/KG ORAL LD50 RAT; 4000-10200 MG/KG
LD50/ORAL/MOUSE:
5500 MG/KG (RTECS)
5890-13400 MG/KG (EU COMMISSION IUCLID DATA SET)
LD50/DERMAL/RABBIT:
>2000 MG/KG (EU COMMISSION IUCLID DATASET)
9530 UL/KG (RTECS)
LD50/DERMAL/RAT: 10600 MG/KG DERMAL LD50
LC50/INHALATION/RAT: >200 MG/M3 4H (RTECS)
LC50/INHALATION/MOUSE: >200 MG/M3 2H (RTECS)
OTHER LD50 OR LC50 INFORMATION:
6610 MG/KG ORAL LD50 GUINEA PIG
5500 MG/KG ORAL LD50 DOG
1650 MG/KG ORAL LD50 CAT
LETHAL DOSE IN ADULT HUMANS IS 1-1.5 ML/KG OR 1110-1665 MG/KG
(MINNESOTA POISON CONTROL SYSTEM)
PRODUCT INFORMATION:
LD50/ORAL/RAT:
VALUE - ACUTE TOXICITY: 4000 MG/KG
LD50/ORAL/MOUSE:
VALUE - ACUTE TOX: 5500 MG/KG
LD50/DERMAL/RABBIT:
VALUE - ACUTE TOXICITY: >2000 MG/KG
LD50/DERMAL/RAT:
VALUE - ACUTE TOX: 10600 MG/KG
LC50/INHALATION/RAT:
VALUE-VAPOR: NO INFORMATION AVAILABLE
VALUE-GAS: NO INFORMATION AVAILABLE
VALUE-DUST/MIST: >2000 MG/M3 (RAT, 4 HR)
LC50/INHALATION/MOUSE:
VALUE-VAPOR: NO INFORMATION AVAILABLE
VALUE - GAS: NO INFORMATION AVAILABLE
VALUE - DUST/MIST: >2000 MG/M3 2H
SYMPTOMS:
SKIN CONTACT:
MILD SKIN IRRITATION. IT MAY BE ABSORBED THROUGH THE SKIN. MAY CAUSE MORE
SEVERE RESPONSE IF SKIN IS ABRADED. A SINGLE PROLONGED EXPOSURE IS NOT
LIKELY TO RESULT IN MATERIAL BEING ABSORBED THROUGH THE SKIN IN HARMFUL
AMOUNTS. MASSIVE CONTACT WITH DAMAGED SKIN MAY RESULT IN ABSORPTION OF
POTENTIALLY HARMFUL AMOUNTS.
EYE CONTACT:
CAUSES EYE IRRITATION. VAPORS OR MIST MAY CAUSE MAY CAUSE TEMPORARY EYE
IRRITATION (MILD CONJUNTIVAL INFLAMMATION) AND LACRIMATION. CORNEAL INJURY
IS UNLIKELY.
INHALATION:
MAY CAUSE IRRITATION OF RESPIRATORY TRACT. AT ROOM TEMPERATURE, VAPORS ARE
MINIMAL DUE TO LOW VAPOR PRESSURE. WITH GOOD VENTILATION, A SINGLE EXPOSURE
IS NOT EXPECTED TO CAUSE ADVERSE EFFECTS. IF THE MATERIAL IS HEATED OR
MISTED, OR USED IN AN AREA THAT IS POORLY VENTILATED, VAPOR OR MIST MAY
ACCUMULATE AND CONCENTRATIONS MAY BE ATTAINED THAT ARE SUFFICIENT TO CAUSE
RESPIRATORY TRACT AND MUCOUS MEMBRANE IRRITATION. SYMPTOMS MAY INCLUDE THE
FOLLOWING:
A BURNING SENSATION IN THE THROAT, COUGHING, HEADACHE. INHALATION OF HIGH
CONCENTRATIONS OF MIST OR VAPORS MAY CAUSE HYPERMOTILITY, DIARRHEA. IT MAY
ALSO AFFECT THE KIDNEYS, AND CENTRAL NERVOUS SYSTEM (MUSCLE CONTRACTION OR
SPASTICITY). INHALATION OF HIGH CONCENTRATIONS OF ETHYLENE GLYCOL VAPOR MAY
ALSO CAUSE EPISODES OF NYSTAGMUS, AND LOSS OF CONCIOUSNESS.
INGESTION:
HARMFUL IF SWALLOWED. IT IS RAPIDLY ABSORBED FROM THE GASTROINTESTINAL
TRACT. ORAL TOXICITY IS EXPECTED TO BE MODERATE IN HUMANS THOUGH TESTS
WITH ANIMALS SHOW A LOWER DEGREE OF TOXICITY. INGESTION MAY CAUSE NAUSEA,
VOMITING, DIARRHEA. MAY CAUSE ABDOMINAL PAIN. IT CAN AFFECT
BEHAVIOR/CENTRAL NERVOUS SYSTEM WITHIN 0.5 TO 12 HOURS AFTER INGESTION. A
TRANSIENT INEBRIATION WITH EXCITEMENT, STUPOR, HEADACHE, SLURRED SPEECH,
ATAXIA, SOMNOLENCE, AND EUHORIA, SIMILAR TO ETHANOL INTOXICATION, CAN OCCUR
WITHIN THE FIRST SEVERAL HOURS. AS THE ETHYLENE GLYCOL IS METABOLILZED,
METABOLIC ACIDOSIS AND FURTHER CENTRAL NERVOUS SYSTEM DEPRESSION
(CONVULSIONS, MUSCLE WEAKNESS) DEVELOP. SERIOUS INTOXICATION MAY DEVELOP
CAUSING COMA, HYPTONIA, HYPOREFLEXIA, AND LESS COMMONLY SEIZURES. 12 TO
24 HOURS AFTER INGESTION, CARDIOVASCULAR SYMPTOMS SUCH AS TACHYCARDIA AND
HYPERTENSION MAY OCCUR AS WELL AS HYPOXIA, HYPERVENTILATION, CARDIOMEGALY,
MYOCARDITIS PROGRESSING TO CARDIOGENIC SHOCK AND CONGESTIVE HEART FAILURE.
24 TO 72 HOURS AFTER INGESTION, ALBUMINURIA, OLIGURIA, HEMATURIA,
PROTEINURIA, ACUTE TUBULAR NECROSIS, RENAL FAILURE AND OCCASIONALLY BONE
MARROW SUPRESSION OCCUR. CALCIUM OXALATE CRYSTALS MAY BE DETECTED, BUT
ABSENCE OF THEM DOES NOT RULE OUT THE DIAGNOSIS. HYPOCALCEMIA MAY OCCUR.
SERIOUS HEPATIC INJURY IS UNCOMMON. MYDRIASIS INVOLUNTARY EYE
MOVEMENTS(NYASTIGMUS) AND EFFECTS ON THE BLOOD (PANCYTOPENIA, LEUKOCYTOSIS,
LYMPHOCYTOSIS) MAY ALSO OCCUR.
ASPIRATION HAZARD: NO INFORMATION AVAILABLE.
DELAYED AND IMMEDIATE EFFECTS AS WELL AS CHRONIC EFFECTS FROM SHORT AND
LONG-TERM EXPOSURE:
CHRONIC TOXICITY:
PROLONGED OR REPEATED INHALATION MAY CAUSE HEADACHE. PROLONGED OR REPEATED
INHALATION MAY AFFECT THE LIVER. PROLONGED OR REPEATED INHALATION MAY
AFFECT THE KIDNEYS. PROLONGED OR REPEATED INHALATION MAY AFFECT THE BRAIN.
PROLONGED OR REPEATED INHALATION MAY AFFECT METABOLISM (WEIGHT LOSS).
PROLONGED OR REPEATED INGESTION MAY CAUSE WEIGHT LOSS. PROLONGED OR
REPEATED INHALATION MAY CAUSE CENTRAL NERVOUS SYSTEM EFFECTS. PROLONGED OR
REPEATED INHALATION MAY AFFECT RESPIRATION. PROLONGED OR REPEATED
INHALATION MAY CAUSE MORE PRONOUNCED IRRITATION OF THE UPPER RESPIRATORY
TRACT. REPEATED EXCESSIVE INGESTION MAY AFFECT THE KIDNEYS (KIDNEY DAMAGE,
WITH OR WITHOUT DEPOSITS OF CALCIUM OXALATE IN THE KIDNEYS), AND THE LIVER
(HEPATITIS, HEPATOCELLULAR NECROSIS). PROLONGED OR REPEATED INGESTION MAY
AFFECT THE BLOOD (CHANGES IN SERUM COMPOSITION).
SENSITIZATION: NO INFORMATION AVAILABLE.
MUTAGENIC EFFECTS:
MAY AFFECT GENETIC MATERIAL
MUTAGENIC EFFECTS IN MAMMALIAN SOMATIC CELLS
EXPERIMENTS WITH ANIMAL LYMPHOCYTES HAVE SHOWN MUTAGENIC EFFECTS
CARCINOGENIC EFFECTS: NOT CLASSIFIABLE AS A HUMAN CARCINOGEN.
COMPONENT CAS NO IARC ACGIH - CARCINOGENS NTP
ETHYLENE GLYCOL 107-21-1 NOT LISTED A4 NOT NOT LISTED
CLASSIFIABLE
AS A HUMAN
CARCINOGEN
COMPONENT OSHA HCS - AUSTRALIA - AUSTRALIA -
CARCINOGENS NOTIFIABLE PROHIBITED
CARCINOGENIC CARCINOGENIC
SUBSTANCES SUBSTANCES
ETHYLENE GLYCOL NOT LISTED NOT LISTED NOT LISTED
ACGIH (AMERICAN CONFERENCE OF GOVERNMENTAL INDUSTRIAL HYGIENISTS)
IARC (INTERNATIONAL AGENCY FOR RESEARCH ON CANCER)
NTP (NATIONAL TOXICOLOGY PROGRAM)
OSHA (OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION OF THE US DEPARTMENT
OF LABOR)
REPRODUCTIVE TOXICITY: NO DATA IS AVAILABLE
REPRODUCTIVE EFFECTS:
MAY CAUSE ADVERSE REPRODUCTIVE EFFECTS BASED ON ANIMAL DATA
IT HAS NOT BEEN SHOWN TO AFFECT REPRODUCTION IN HUMANS
DEVELOPMENTAL EFFECTS:
MAY CAUSE ADVERSE DEVELOPMENTAL EFFECTS BASED ON ANIMAL DATA
NO INFORMATION ON DEVELOPMENTAL TOXICITY EFFECTS ON HUMANS WAS FOUND
TERATOGENIC EFFECTS:
MAY CAUSE BIRTH DEFECTS (TERATOGENIC EFFECTS) BASED ON ANIMAL TEST DATA
THERE ARE NO ADEQUATE AND WELL-CONTROLLED STUDIES IN HUMANS
SPECIFIC TARGET ORGAN TOXICITY:
STOT - SINGLE EXPOSURE: NO INFORMATION AVAILABLE.
STOT - REPEATED EXPOSURE: NO INFORMATION AVAILABLE.
TARGET ORGANS: KIDNEYS. CENTRAL NERVOUS SYSTEM. BRAIN. RESPIRATORY SYSTEM.
| 12. ECOLOGICAL INFORMATION | |
ECOTOXICITY:
ECOTOXICITY EFFECTS: AQUATIC ENVIRONMENT.
ETHYLENE GLYCOL - 107-21-1:
ALGAE/AQUATIC PLANTS FISH:
EC50: 6500 - 13000 MG/L (96H, PSEUDOKIRCHNERIELLA SUBCAPITATA)
LC50: =41000 MG/L (96H, ONCORHYNCHUS MYKISS)
LC50: 14 - 18 ML/L (96H, ONCORHYNCHUS MYKISS)
LC50: =27540 MG/L (96H, LEPOMIS MACROCHIRUS)
LC50: =40761 MG/L (96H, ONCORHYNCHUS MYKISS)
LC50: 40000 - 60000 MG/L (96H, PIMEPHALES PROMELAS)
LC50: =16000 MG/L (96H, POECILIA RETICULATA)
CRUSTACEA:
EC50: =46300 MG/L (48H, DAPHNIA MAGNA)
PERSISTENCE AND DEGRADABILITY: READILY BIODEGRADABLE
BIOACCUMULATIVE POTENTIAL: NO INFORMATION AVAILABLE.
MOBILITY IN SOIL: NO INFORMATION AVAILABLE
OTHER ADVERSE EFFECTS: NO INFORMATION AVAILABLE.
| 13. DISPOSAL CONSIDERATIONS | |
DISPOSAL METHODS:
WASTE FROM RESIDUES / UNUSED PRODUCTS:
WASTE MUST BE DISPOSED OF IN ACCORDANCE WITH FEDERAL, STATE AND LOCAL
REGULATION.
CONTAMINATED PACKAGING:
EMPTY CONTAINERS SHOULD BE TAKEN FOR LOCAL RECYCLING, RECOVERY OR WASTE
DISPOSAL
COMPONENT CAS NO RCRA - F RCRA - K RCRA - P RCRA - U
SERIES SERIES SERIES SERIES
WASTES WASTES WASTES WASTES
ETHYLENE GLYCOL 107-21-1 NONE NONE NONE NONE
| 14. TRANSPORT INFORMATION | |
DOT:
UN-NO: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
HAZARD CLASS: NO INFORMATION AVAILABLE
SUBSIDIARY CLASS: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
EMERGENCY RESPONSE GUIDE NUMBER: NO INFORMATION AVAILABLE
MARINE POLLUTANT: NO DATA AVAILABLE
DOT RQ (LBS): NO INFORMATION AVAILABLE
SPECIAL PROVISIONS: NO INFORMATION AVAILABLE
SYMBOL(S): NO INFORMATION AVAILABLE
DESCRIPTION: NO INFORMATION AVAILABLE
TDG (CANADA):
UN-NO: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
HAZARD CLASS: NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
MARINE POLLUTANT: NO INFORMATION AVAILABLE
DESCRIPTION: NO INFORMATION AVAILABLE
ADR:
UN NUMBER: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
TRANSPORT HAZARD CLASS(ES): NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
IMDG:
UN-NO: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
HAZARD CLASS: NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
MARINE POLLUTANT: NO INFORMATION AVAILABLE
RID:
UN NUMBER: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
TRANSPORT HAZARD CLASS(ES): NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
ICAO (AIR):
UN-NO: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
HAZARD CLASS: NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
IATA:
UN NUMBER: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
TRANSPORT HAZARD CLASS(ES): NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
PRECAUTIONARY STATEMENTS - RESPONSE: NO INFORMATION AVAILABLE
SPECIAL PROVISIONS: NO INFORMATION AVAILABLE
| 15. REGULATORY INFORMATION | |
INTERNATIONAL INVENTORIES:
COMPONENT CAS NO U.S. TSCA KOREA KECL PHILIPPINES
(PICCS)
ETHYLENE GLYCOL 107-21-1 PRESENT PRESENT PRESENT
ACTIVE KE-13169
COMPONENT JAPAN ENCS CHINA IECSC AUSTRALIA EINECS-NO.
(AICS)
ETHYLENE GLYCOL PRESENT PRESENT PRESENT PRESENT
(2)-230 203-473-3
U.S. REGULATIONS:
ETHYLENE GLYCOL:
MASSACHUSETTS RTK: PRESENT
NEW JERSEY RTK HAZARDOUS SUBSTANCE LIST: 0878
NEW JERSEY (EHS) LIST: 0878 500 LB TPQ
NEW JERSEY - DISCHARGE PREVENTION - LIST OF HAZARDOUS SUBSTANCES: PRESENT
PENNSYLVANIA RTK: ENVIRONMENTAL HAZARD
PENNSYLVANIA RTK - ENVIRONMENTAL HAZARD LIST: PRESENT
MINNESOTA - HAZARDOUS SUBSTANCE LIST: PRESENT
NEW YORK RELEASE REPORTING - LIST OF HAZARDOUS SUBSTANCES: 1 LB RQ
LOUISANA REPORTABLE QUANTITY LIST FOR POLLUTANTS:
5000 LB FINAL RQ
2270 KG FINAL RQ
CALIFORNIA DIRECTORS LIST OF HAZARDOUS SUBSTANCES: PRESENT
CALIFORNIA PROP. 65: SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986.
CHEMICALS KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER:
THIS PRODUCT DOES NOT CONTAIN A CHEMICAL REQUIRING A WARNING UNDER
CALIFORNIA PROP. 65. (SEE TABLE BELOW)
CHEMICALS KNOWN TO THE STATE OF CALIFORNIA TO CAUSE REPRODUCTIVE TOXICITY:
THIS PRODUCT DOES NOT CONTAIN A CHEMICAL REQUIRING A WARNING UNDER
CALIFORNIA PROP. 65. (SEE TABLE BELOW)
COMPONENT CAS NO CARCINOGEN DEVELOPMENTAL MALE FEMALE
TOXICITY REPRODUCTIVE REPRODUCTIVE
TOXICITY TOXICITY
ETHYLENE 107-21-1 NOT LISTED DEVELOPMENTAL NOT LISTED NOT LISTED
GLYCOL TOXICITY
CERCLA/SARA:
COMPONENT CAS NO CERCLA - HAZARDOUS SECTION 302 EXTREMELY
SUBSTANCES AND HAZARDOUS SUBSTANCES
THEIR REPORTABLE AND TPQS
QUANTITIES
ETHYLENE GLYCOL 107-21-1 5000 LB FINAL RQ NONE
2270 KG FINAL RQ
COMPONENT SECTION 302 SECTION 313 - SECTION 313 -
EXTREMELY CHEMICAL CATEGORY REPORTING
HAZARDOUS DE MINIMIS
SUBSTANCES
AND RQS
ETHYLENE GLYCOL NONE NONE 1.0% DE MINIMIS
CONCENTRATION
U.S. TSCA:
COMPONENT CAS NO TSCA SECTION 5(A)2 - TSCA 8(D) - HEALTH
CHEMICALS WITH AND SAFETY REPORTING
SIGNIFICANT NEW USE
RULES (SNURS)
ETHYLENE GLYCOL 107-21-1 NOT APPLICABLE NOT APPLICABLE
CANADA:
WHIMIS 2015 - GHS CLASSIFICATIONS:
WHMIS 2015 HAZARD CLASSIFICATION INFORMATION:
COMPONENT WHMIS 2015 HAZARD CLASSIFICATION
ETHYLENE GLYCOL ACUTE TOXICITY - ORAL - CATEGORY 4:
107-21-1 H302: HARMFUL IF SWALLOWED.
(100)
SPECIFIC TARGET ORGAN TOXICITY - SINGLE
EXPOSURE - CATEGORY 3:
H335: MAY CAUSE RESPIRATORY IRRITATION.
CANADA HAZARDOUS PRODUCTS REGULATION:
THIS PRODUCT HAS BEEN CLASSIFIED ACCORDING TO THE HAZARD CRITERIA OF
THE HPR (HAZARDOUS PRODUCTS REGULATION) AND THE SDS CONTAINS ALL OF
THE INFORMATION REQUIRED BY THE HPR
DSL/NDSL:
COMPONENT CAS NO CANADA (DSL) CANADA (NDSL)
ETHYLENE GLYCOL 107-21-1 PRESENT NOT LISTED
COMPONENT CAS NO CEPA SCHEDULE I - TOXIC SUBSTANCES
ETHYLENE GLYCOL 107-21-1 NOT LISTED
COMPONENT CAS NO CEPA - 2010 GREENHOUSE GASES SUBJECT
TO MANDATORY REPORTING
ETHYLENE GLYCOL 107-21-1 NOT LISTED
EU CLASSIFICATION:
EU GHS - SV - CLP 1272/2008:
COMPONENT CAS NO EU GHS - SV - CLP (1272/2008)
ETHYLENE GLYCOL 107-21-1 ACUTE TOXICITY - ORAL - ACUTE TOX. 4:
H302:
HARMFUL IF SWALLOWED.
(MINIMUM CLASSIFICATION) 603-027-00-1
EU - CLP (1272/2008):
R-PHRASE(S):
R22: HARMFUL IF SWALLOWED
S-PHRASE(S):
S 2: KEEP OUT OF THE REACH OF CHILDREN.
COMPONENT CAS NO CLASSIFICATION CONCENTRATION SAFETY PHRASES
LIMITS
ETHYLENE GLYCOL 107-21-1 XN; R22 NO INFORMATION S2
THE PRODUCT IS CLASSIFIED IN ACCORDANCE WITH ANNEX VI TO DIRECTIVE
67/548/EEC:
INDICATION OF DANGER: XN - HARMFUL
| 16. OTHER INFORMATION | |
PREPARATION DATE: 3/20/2015
REVISION DATE 11/19/2019
PREPARED BY: SONIA OWEN
DISCLAIMER:
ALL CHEMICALS MAY POSE UNKNOWN HAZARDS AND SHOULD BE USED WITH CAUTION.
THIS SAFETY DATA SHEET (SDS) APPLIES ONLY TO THE MATERIAL AS PACKAGED. IF
THIS PRODUCT IS COMBINED WITH OTHER MATERIALS, DETERIORATES, OR BECOMES
CONTAMINATED, IT MAY POSE HAZARDS NOT MENTIONED IN THIS SDS. THE PHYSICAL
PROPERTIES REPORTED IN THIS SDS ARE OBTAINED FROM THE LITERATURE AND DO
NOT CONSTITUTE PRODUCT SPECIFICATIONS. INFORMATION CONTAINED HEREIN DOES
NOT CONSTITUTE A WARRANTY, WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY,
MERCHANTABILITY OR FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. SPECTRUM
CHEMICALS & LABORATORY PRODUCTS, INC. ASSUMES NO RESPONSIBILITY FOR RESULTS
OBTAINED OR FOR INCIDENTAL OR CONSEQUENTIAL DAMAGES, INCLUDING LOST
PROFITS, ARISING FROM THE USE OF THESE DATA. NO WARRANTY AGAINST
INFRINGEMENT OF ANY PATENT, COPYRIGHT OR TRADEMARK IS MADE OR IMPLIED. IT
SHALL BE THE USER'S RESPONSIBILITY TO DEVELOP PROPER METHODS OF HANDLING
AND PERSONAL PROTECTION BASED ON THE ACTUAL CONDITIONS OF USE. WHILE THIS
SDS IS BASED ON TECHNICAL DATA JUDGED TO BE RELIABLE, SPECTRUM ASSUMES NO
RESPONSIBILITY FOR THE COMPLETENESS OR ACCURACY OF THE INFORMATION
CONTAINED HEREIN.