| Common Name: | 1-METHYL-2-PYRROLIDINONE, REAGENT, ACS |
| Manufacturer: | SPECTRUM CHEMICALS & LABORATORY PRODUCTS |
| SDS Revision Date: | 11/30/2018 |
| SDS Format: | No Format Specified |
| Item Number(s): | 6NNC3 |
| Manufacturer Model Number(s): |
SDS Table of Contents
Click the desired link below to jump directly to that section in the SDS.
SPECTRUM(R*)
S
ISO 9001-2008 REGISTERED
SAFETY DATA SHEET
PREPARATION DATE: 06/03/2015
REVISION DATE: 11/30/2018
REVISION NUMBER: G4
| 1. IDENTIFICATION |  |
PRODUCT IDENTIFIER:
PRODUCT CODE: M1280
PRODUCT NAME: 1-METHYL-2-PYRROLIDINONE, REAGENT, ACS
OTHER MEANS OF IDENTIFICATION:
SYNONYMS:
1-METHYL-2-PYRROLIDINONE
1-METHYL-2-PYRROLIDONE
1-METHYL-5-PYRROLIDINONE
M-PYROL
1-METHYLAZACYCLOPENTAN-2-ONE
N-METHYL-GAMMA-BUTYROLACTAM
1-METHYLPYRROLIDINONE
1-METHYLPYRROLIDONE
2-PYRROLIDINONE, 1-METHYL-
METHYLPYRROLIDONE
METHYL PYRROLIDONE
N-METHYL-2-PYRROLIDINONE
N-METHYL-2-PYRROLIDONE
N-METHYL-ALPHA-PYRROLIDONE
N-METHYLPYRROLIDINONE
N-METHYLPYRROLIDONE
NMP
CAS #: 872-50-4
RTECS #: UY5790000
CI#: NOT AVAILABLE
RECOMMENDED USE OF THE CHEMICAL AND RESTRICTIONS ON USE:
RECOMMENDED USE: SOLVENT.
USES ADVISED AGAINST: NO INFORMATION AVAILABLE
SUPPLIER:
SPECTRUM CHEMICAL MFG. CORP
14422 SOUTH SAN PEDRO ST.
GARDENA, CA 90248
(310) 516-8000
ORDER ONLINE AT: HTTPS://WWW.SPECTRUMCHEMICAL.COM
EMERGENCY TELEPHONE NUMBER:
CHEMTREC: 1-800-424-9300
CONTACT PERSON: MARTIN LABENZ (WEST COAST)
CONTACT PERSON: IBAD TIRMIZ (EAST COAST)
| 2. HAZARDS IDENTIFICATION | |
CLASSIFICATION:
THIS CHEMICAL IS CONSIDERED HAZARDOUS BY THE 2012 OSHA HAZARD COMMUNICATION
STANDARD (29 CFR 1910.1200)
CONSIDERED A DANGEROUS SUBSTANCE OR MIXTURE ACCORDING TO THE GLOBALLY
HARMONIZED SYSTEM (GHS):
SKIN CORROSION/IRRITATION: CATEGORY 2
SERIOUS EYE DAMAGE/EYE IRRITATION: CATEGORY 2A
REPRODUCTIVE TOXICITY: CATEGORY 1B
SPECIFIC TARGET ORGAN TOXICITY (SINGLE EXPOSURE): CATEGORY 3
FLAMMABLE LIQUIDS: CATEGORY 4
LABEL ELEMENTS:
DANGER
HAZARD STATEMENTS:
CAUSES SKIN IRRITATION
CAUSES SERIOUS EYE IRRITATION
MAY DAMAGE FERTILITY OR THE UNBORN CHILD
MAY CAUSE RESPIRATORY IRRITATION
COMBUSTIBLE LIQUID
EXCLAMATION MARK
HEALTH HAZARD
HAZARDS NOT OTHERWISE CLASSIFIED (HNOC): NOT APPLICABLE
OTHER HAZARDS: MAY BE HARMFUL IN CONTACT WITH SKIN
PRECAUTIONARY STATEMENTS - PREVENTION:
OBTAIN SPECIAL INSTRUCTIONS BEFORE USE
DO NOT HANDLE UNTIL ALL SAFETY PRECAUTIONS HAVE BEEN READ AND UNDERSTOOD
WASH FACE, HANDS AND ANY EXPOSED SKIN THOROUGHLY AFTER HANDLING
WEAR PROTECTIVE GLOVES/PROTECTIVE CLOTHING/EYE PROTECTION/FACE PROTECTION
AVOID BREATHING DUST/FUME/GAS/MIST/VAPORS/SPRAY
USE ONLY OUTDOORS OR IN A WELL-VENTILATED AREA
KEEP AWAY FROM HEAT/SPARKS/OPEN FLAMES/HOT SURFACES. - NO SMOKING
KEEP COOL
PRECAUTIONARY STATEMENTS - RESPONSE:
IF EXPOSED OR CONCERNED: GET MEDICAL ADVICE/ATTENTION
IN CASE OF FIRE: USE CO2, DRY CHEMICAL, OR FOAM TO EXTINGUISH.
IF IN EYES:
RINSE CAUTIOUSLY WITH WATER FOR SEVERAL MINUTES. REMOVE CONTACT LENSES, IF
PRESENT AND EASY TO DO. CONTINUE RINSING.
IF EYE IRRITATION PERSISTS: GET MEDICAL ADVICE/ATTENTION.
IF ON SKIN: WASH WITH PLENTY OF WATER
IF SKIN IRRITATION OCCURS: GET MEDICAL ADVICE/ATTENTION
TAKE OFF CONTAMINATED CLOTHING AND WASH IT BEFORE REUSE
IF INHALED: REMOVE PERSON TO FRESH AIR AND KEEP COMFORTABLE FOR BREATHING.
PRECAUTIONARY STATEMENTS - STORAGE:
STORE LOCKED UP
STORE IN A WELL-VENTILATED PLACE. KEEP CONTAINER TIGHTLY CLOSED
PRECAUTIONARY STATEMENTS - DISPOSAL:
DISPOSE OF CONTENTS/CONTAINER TO AN APPROVED WASTE DISPOSAL PLANT
| 3. COMPOSITION/INFORMATION ON INGREDIENTS | |
FORMULA CAS NO WEIGHT-%
N-METHYL-2-PYRROLIDINONE 872-50-4 100
| 4. FIRST AID MEASURES | |
FIRST AID MEASURES:
GENERAL ADVICE:
NATIONAL CAPITAL POISON CENTER IN THE UNITED STATES CAN PROVIDE ASSISTANCE
IF YOU HAVE A POISON EMERGENCY AND NEED TO TALK TO A POISON SPECIALIST.
CALL 1-800-222-1222.
SKIN CONTACT:
WASH OFF IMMEDIATELY WITH SOAP AND PLENTY OF WATER REMOVING ALL
CONTAMINATED CLOTHING AND SHOES. GET MEDICAL ATTENTION. IF SKIN IRRITATION
PERSISTS, CALL A PHYSICIAN.
EYE CONTACT: FLUSH EYES WITH WATER FOR 15 MINUTES. GET MEDICAL ATTENTION.
INHALATION:
MOVE TO FRESH AIR. IF NOT BREATHING, GIVE ARTIFICIAL RESPIRATION. IF
BREATHING IS DIFFICULT, GIVE OXYGEN. GET MEDICAL ATTENTION.
INGESTION:
DO NOT INDUCE VOMITING WITHOUT MEDICAL ADVICE. NEVER GIVE ANYTHING BY MOUTH
TO AN UNCONSCIOUS PERSON. OBTAIN MEDICAL ATTENTION.
MOST IMPORTANT SYMPTOMS AND EFFECTS, BOTH ACUTE AND DELAYED:
SYMPTOMS:
IRRITATING TO EYES AND SKIN
IRRITATING TO RESPIRATORY SYSTEM
MAY CAUSE AN ALLERGIC SKIN REACTION
MAY BE ABSORBED THROUGH THE SKIN IN HARMFUL AMOUNTS
INGESTION MAY CAUSE GASTROINTESTINAL IRRITATION, NAUSEA, VOMITING, AND
DIARRHEA
INDICATION OF ANY IMMEDIATE MEDICAL ATTENTION AND SPECIAL TREATMENT NEEDED:
NOTES TO PHYSICIAN: TREAT SYMPTOMATICALLY.
PROTECTION OF FIRST-AIDERS:
FIRST-AID PROVIDERS:
AVOID EXPOSURE TO BLOOD OR BODY FLUIDS. WEAR GLOVES AND OTHER NECESSARY
PROTECTIVE CLOTHING. DISPOSE OF CONTAMINATED CLOTHING AND EQUIPMENT AS
BIO-HAZARDOUS WASTE.
| 5. FIRE-FIGHTING MEASURES | |
EXTINGUISHING MEDIA:
SUITABLE EXTINGUISHING MEDIA:
DRY CHEMICAL. CARBON DIOXIDE (CO2). WATER SPRAY MIST OR FOAM.
UNSUITABLE EXTINGUISHING MEDIA:
HIGH VOLUME WATER JET. DO NOT USE A SOLID (STRAIGHT) WATER STREAM AS IT
MAY SCATTER AND SPREAD FIRE.
SPECIFIC HAZARDS ARISING FROM THE CHEMICAL:
HAZARDOUS COMBUSTION PRODUCTS:
CARBON MONOXIDE, CARBON DIOXIDE. NITROGEN OXIDES (NOX).
SPECIFIC HAZARDS:
COMBUSTIBLE MATERIAL. MAY BE IGNITED BY HEAT, SPARKS OR FLAMES. VAPORS MAY
FORM EXPLOSIVE MIXTURES WITH AIR. MOST VAPORS ARE HEAVIER THAN AIR. THEY
WILL SPREAD ALONG THE GROUND AND COLLECT IN LOW OR CONFINED AREAS
(SEWERS, BASEMENTS, TANKS). CONTAINER EXPLOSION MAY OCCUR UNDER FIRE
CONDITIONS OR WHEN HEATED. IT IS COMBUSTIBLE WHEN EXPOSED TO POWERFUL
OXIDIZERS.
SPECIAL PROTECTIVE ACTIONS FOR FIREFIGHTERS:
SPECIFIC METHODS:
WATER MIST MAY BE USED TO COOL CLOSED CONTAINERS FOR LARGER FIRES, USE
WATER SPRAY OR FOG. COOL CONTAINERS WITH FLOODING QUANTITIES OF WATER UNTIL
WELL AFTER FIRE IS OUT
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS:
AS IN ANY FIRE, WEAR SELF-CONTAINED BREATHING APPARATUS PRESSURE-DEMAND,
MSHA/NIOSH (APPROVED OR EQUIVALENT) AND FULL PROTECTIVE GEAR
| 6. ACCIDENTAL RELEASE MEASURES | |
PERSONAL PRECAUTIONS, PROTECTIVE EQUIPMENT AND EMERGENCY PROCEDURES:
PERSONAL PRECAUTIONS:
ENSURE ADEQUATE VENTILATION. KEEP PEOPLE AWAY FROM AND UPWIND OF
SPILL/LEAK. AVOID CONTACT WITH SKIN, EYES AND CLOTHING. USE PERSONAL
PROTECTIVE EQUIPMENT. DO NOT TOUCH DAMAGED CONTAINERS OR SPILLED MATERIAL
UNLESS WEARING APPROPRIATE PROTECTIVE CLOTHING. USE SPARK-PROOF TOOLS AND
EXPLOSION-PROOF EQUIPMENT. ALL EQUIPMENT USED WHEN HANDLING THE PRODUCT
MUST BE GROUNDED. REMOVE ALL SOURCES OF IGNITION.
ENVIRONMENTAL PRECAUTIONS:
PREVENT FURTHER LEAKAGE OR SPILLAGE IF SAFE TO DO SO. PREVENT PRODUCT FROM
ENTERING DRAINS. PREVENT ENTRY INTO WATERWAYS, SEWERS, BASEMENTS OR
CONFINED AREAS.
METHODS AND MATERIAL FOR CONTAINMENT AND CLEANING UP:
METHODS FOR CONTAINMENT:
STOP LEAK IF YOU CAN DO IT WITHOUT RISK. ABSORB SPILL WITH INERT MATERIAL
(E.G. VERMICULITE, DRY SAND OR EARTH), THEN PLACE IN A SUITABLE CHEMICAL
WASTE CONTAINER.
METHODS FOR CLEANING UP:
USE APPROPRIATE TOOLS TO PUT THE SPILLED MATERIAL IN A SUITABLE CHEMICAL
WASTE DISPOSAL CONTAINER. USE CLEAN NON-SPARKING TOOLS TO COLLECT ABSORBED
MATERIAL. CLEAN CONTAMINATED SURFACE THOROUGHLY.
| 7. HANDLING AND STORAGE | |
PRECAUTIONS FOR SAFE HANDLING:
TECHNICAL MEASURES/PRECAUTIONS:
PROVIDE SUFFICIENT AIR EXCHANGE AND/OR EXHAUST IN WORK ROOMS. REMOVE ALL
SOURCES OF IGNITION. TO AVOID IGNITION OF VAPORS BY STATIC ELECTRICITY
DISCHARGE, ALL METAL PARTS OF THE EQUIPMENT MUST BE GROUNDED. KEEP AWAY
FROM INCOMPATIBLE MATERIALS.
SAFE HANDLING ADVICE:
WEAR PERSONAL PROTECTIVE EQUIPMENT. AVOID CONTACT WITH SKIN, EYES AND
CLOTHING. KEEP AWAY FROM HEAT AND SOURCES OF IGNITION. DO NOT INGEST. DO
NOT BREATHE VAPORS OR SPRAY MIST. HANDLE IN ACCORDANCE WITH GOOD INDUSTRIAL
HYGIENE AND SAFETY PRACTICE.
CONDITIONS FOR SAFE STORAGE, INCLUDING ANY INCOMPATIBILITIES:
TECHNICAL MEASURES/STORAGE CONDITIONS:
HYGROSCOPIC. KEEP CONTAINER TIGHTLY CLOSED IN A DRY AND WELL-VENTILATED
PLACE. STORE AT ROOM TEMPERATURE IN THE ORIGINAL CONTAINER. KEEP AWAY FROM
HEAT AND SOURCES OF IGNITION. STORE IN A SEGREGATED AND APPROVED AREA.
STORE AWAY FROM INCOMPATIBLE MATERIALS. STORE UNDER INERT GAS.
INCOMPATIBLE MATERIALS:
OXIDIZING AGENTS
REDUCING AGENTS
ACIDS
BASES
| 8. EXPOSURE CONTROLS/PERSONAL PROTECTION | |
CONTROL PARAMETERS:
NATIONAL OCCUPATIONAL EXPOSURE LIMITS:
UNITED STATES:
FORMULA CAS NO OSHA NIOSH ACGIH AIHA WEEL
N-METHYL-2-PYRROLIDINONE 872-50-4 NONE NONE NONE 10 PPM TWA
CANADA:
FORMULA CAS NO CANADA - CANADA - CANADA - CANADA -
ALBERTA BRITISH ONTARIO QUEBEC
COLUMBIA
N-METHYL-2- 872-50-4 NONE NONE 400 MG/M3 NONE
PYRROLIDINONE TWA
AUSTRALIA AND MEXICO:
FORMULA CAS NO AUSTRALIA MEXICO
N-METHYL-2-PYRROLIDINONE 872-50-4 75 PPM STEL NONE
309 MG/M3 STEL
25 PPM TWA
103 MG/M3 TWA
APPROPRIATE ENGINEERING CONTROLS:
ENGINEERING MEASURES TO REDUCE EXPOSURE:
ENSURE ADEQUATE VENTILATION PROVIDE EXHAUST VENTILATION OR OTHER
ENGINEERING CONTROLS TO KEEP THE AIRBORNE CONCENTRATIONS OF VAPORS AND
MIST BELOW THEIR RESPECTIVE THRESHOLD LIMIT VALUE.
INDIVIDUAL PROTECTION MEASURES, SUCH AS PERSONAL PROTECTIVE EQUIPMENT:
PERSONAL PROTECTIVE EQUIPMENT:
EYE PROTECTION: GOGGLES
SKIN AND BODY PROTECTION:
LONG SLEEVED CLOTHING
CHEMICAL RESISTANT APRON
GLOVES
RESPIRATORY PROTECTION:
VAPOR RESPIRATOR. BE SURE TO USE AN APPROVED/CERTIFIED RESPIRATOR OR
EQUIVALENT. RESPIRATORY PROTECTION IS NOT NECESSARY FOR NORMAL HANDLING.
GOOD ROOM VENTILATION OR USE OF LOCAL EXHAUST (FUME HOOD) IS SUFFICIENT.
USE A VAPOR RESPIRATOR UNDER CONDITIONS WHERE EXPOSURE TO THE SUBSTANCE IS
APPARENT (E.G. GENERATION OF HIGH CONCENTRATIONS OF MIST OR VAPOR,
INADEQUATE VENTILATION, DEVELOPMENT OF RESPIRATORY TRACT IRRITATION), AND
ENGINEERING CONTROLS ARE NOT FEASIBLE. BE SURE TO USE AN APPROVED/CERTIFIED
RESPIRATOR OR EQUIVALENT.
HYGIENE MEASURES:
AVOID CONTACT WITH SKIN, EYES AND CLOTHING. WASH HANDS BEFORE BREAKS AND
IMMEDIATELY AFTER HANDLING THE PRODUCT WHEN USING, DO NOT EAT, DRINK OR
SMOKE.
| 9. PHYSICAL AND CHEMICAL PROPERTIES | |
PHYSICAL STATE: LIQUID
APPEARANCE: NO INFORMATION AVAILABLE.
COLOR: COLORLESS. LIGHT YELLOW.
ODOR: MILD. AMINE-LIKE.
TASTE: NO INFORMATION AVAILABLE.
FORMULA: C5-H9-N-O
MOLECULAR/FORMULA WEIGHT (G/MOLE): 99.14
FLAMMABILITY (SOLID, GAS): COMBUSTIBLE
FLASHPOINT (DEG. C/DEG. F):
92.778 DEG. C/199 DEG. F
95.556 DEG. C/204 DEG. F
FLASH POINT TESTED ACCORDING TO:
CLOSED CUP
OPEN CUP
AUTOIGNITION TEMPERATURE (DEG. C/DEG. F): 346.11 DEG. C/655 DEG. F
LOWER EXPLOSION LIMIT (%): 1.3%
UPPER EXPLOSION LIMIT (%): 9.5%
MELTING POINT/RANGE(DEG. C/DEG. F): -24 DEG. C/-11.2 DEG. F
DECOMPOSITION TEMPERATURE(DEG. C/DEG. F): NO INFORMATION AVAILABLE
BOILING POINT/RANGE(DEG. C/DEG. F): 202 DEG. C/395.6 DEG. F
BULK DENSITY: NO INFORMATION AVAILABLE
DENSITY (G/CM3): NO INFORMATION AVAILABLE
SPECIFIC GRAVITY: 1.026
PH: NO INFORMATION AVAILABLE
VAPOR PRESSURE @ 20 DEG. C (KPA):
0.032-0.039 AT 20 DEG. C
0.05 AT 25 DEG. C
EVAPORATION RATE: 0.06 (BUTYL ACETATE = 1)
VAPOR DENSITY: 3.4
VOC CONTENT (G/L): 1026
ODOR THRESHOLD (PPM): NO INFORMATION AVAILABLE
PARTITION COEFFICIENT (N-OCTANOL/WATER): -0.54
VISCOSITY: NO INFORMATION AVAILABLE
MISCIBILITY:
MISCIBLE WITH WATER
MISCIBLE WITH CASTOR OIL
MISCIBLE WITH LOWER ALCOHOLS
MISCIBLE WITH KETONES
MISCIBLE WITH ETHYL ACETATE
MISCIBLE WITH CHLOROFORM
MISCIBLE WITH BENZENE
SOLUBILITY:
MODERATELY SOLUBLE IN ALIPHATIC HYDROCARBONS AND DISSOLVES MANY ORGANIC
AND INORGANIC COMPOUNDS
| 10. STABILITY AND REACTIVITY | |
REACTIVITY:
REACTIVE WITH OXIDIZING AGENTS
REACTIVE WITH ACIDS
REACTS WITH STRONG BASES
REACTS WITH REDUCING AGENTS
HYGROSCOPIC. IT ABSORBS MOISTURE FROM THE AIR
IT REACTS WITH CHLORINATING AGENTS (E.G. COBALT CHLORIDE, THIONYL CHLORIDE,
PHOSPHOROUS OXYCHLORIDE, PENTACHLOROPHOSPHOROUS) TO FORM THE AMIDE
IT REACTS WITH SULFUR AND CARBON DISULFIDE AT HIGH TEMPERATURES AND
PRESSURES
CHEMICAL STABILITY:
STABILITY: HYGROSCOPIC. STABLE UNDER RECOMMENDED STORAGE CONDITIONS.
POSSIBILITY OF HAZARDOUS REACTIONS: HAZARDOUS POLYMERIZATION DOES NOT OCCUR
CONDITIONS TO AVOID:
HEAT. IGNITION SOURCES. INCOMPATIBLE MATERIALS. EXPOSURE TO MOIST AIR.
INCOMPATIBLE MATERIALS:
OXIDIZING AGENTS
REDUCING AGENTS
ACIDS
BASES
HAZARDOUS DECOMPOSITION PRODUCTS:
CARBON MONOXIDE. CARBON DIOXIDE. NITROGEN OXIDES (NOX).
OTHER INFORMATION:
CORROSIVITY: NO INFORMATION AVAILABLE
SPECIAL REMARKS ON CORROSIVITY: NO INFORMATION AVAILABLE
| 11. TOXICOLOGICAL INFORMATION | |
INFORMATION ON LIKELY ROUTES OF EXPOSURE:
PRINCIPAL ROUTES OF EXPOSURE: SKIN. EYES. INHALATION. INGESTION.
ACUTE TOXICITY:
COMPONENT INFORMATION:
N-METHYL-2-PYRROLIDINONE:
CAS NO: 872-50-4
LD50/ORAL/RAT:
3914 MG/KG ORAL LD50 RAT (LOLI; RTECS)
3598 MG/KG (EU CHEMICALS BUREAU IUCLID DATASET)_
LD50/ORAL/MOUSE:
5130 MG/KG (RTECS)
7725 MG/KG (EU CHEMICALS BUREAU IUCLID DATASET)
LD50/DERMAL/RABBIT:
8 G/KG (RTECS; LOLI)
2000-4000 MG/KG (EU CHEMICALS BUREAU IUCLID DATASET)
LD50/DERMAL/RAT: 2500-5000 MG/KG
LC50/INHALATION/RAT:
3.1 MG/L INHALATION LC50 RAT 4 H (LOLI)
3.1-8.8 MG/L 4 H (EU COMMISSION CHEMICALS BUREAU IUCLID DATASET)
LC50/INHALATION/MOUSE: NO INFORMATION AVAILABLE
OTHER LD50 OR LC50 INFORMATION: NO INFORMATION AVAILABLE
PRODUCT INFORMATION:
LD50/ORAL/RAT:
VALUE - ACUTE TOX DERMAL: 3914 MG/KG
LD50/ORAL/MOUSE:
VALUE - ACUTE TOX ORAL: 5130 MG/KG
LD50/DERMAL/RABBIT:
VALUE - ACUTE TOX DERMAL: 2000-4000 MG/KG
LD50/DERMAL/RAT:
VALUE - ACUTE TOX DERMAL: 2500-5000 MG/KG
LC50/INHALATION/RAT:
VALUE-VAPOR: NO INFORMATION AVAILABLE
VALUE-GAS: NO INFORMATION AVAILABLE
VALUE-DUST/MIST: 3.1 MG/L
LC50/INHALATION/MOUSE:
VALUE-VAPOR: NO INFORMATION AVAILABLE
VALUE - GAS: NO INFORMATION AVAILABLE
VALUE - DUST/MIST: NO INFORMATION AVAILABLE
SYMPTOMS:
SKIN CONTACT: CAUSES SKIN IRRITATION.
EYE CONTACT:
CAUSES SERIOUS EYE IRRITATION. MODERATELY IRRITATING TO THE EYES.
INHALATION: IRRITATING TO RESPIRATORY SYSTEM.
INGESTION:
INGESTION MAY CAUSE GASTROINTESTINAL IRRITATION, NAUSEA, VOMITING AND
DIARRHEA. MAY CAUSE ABDOMINAL PAIN.
ASPIRATION HAZARD: NO INFORMATION AVAILABLE.
DELAYED AND IMMEDIATE EFFECTS AS WELL AS CHRONIC EFFECTS FROM SHORT AND
LONG-TERM EXPOSURE:
CHRONIC TOXICITY:
PROLONGED OR REPEATED INHALATION MAY CAUSE DIFFICULTY BREATHING, SHORTNESS
OF BREATH, AND PULMONARY EDEMA. PROLONGED OR REPEATED INHALATION MAY AFFECT
THE KIDNEYS. PROLONGED OR REPEATED INHALATION MAY AFFECT METABOLISM
(WEIGHT LOSS). PROLONGED OR REPEATED INHALATION MAY AFFECT THE BLOOD
(CHANGES IN WHITE BLOOD CELL COUNT). PROLONGED OR REPEATED INGESTION MAY
AFFECT THE SPLEEN. PROLONGED OR REPEATED INGESTION MAY AFFECT THE LIVER,
AND KIDNEYS. PROLONGED OR REPEATED INGESTION MAY AFFECT THE BLOOD (CHANGES
IN SERUM COMPOSITION). PROLONGED OR REPEATED INGESTION MAY AFFECT THE BLOOD
(CHANGES IN PLATELET COUNT). PROLONGED OR REPEATED INHALATION OR INGESTION
MAY AFFECT THE CENTRAL NERVOUS SYSTEM (SOMNOLENCE, MUSCLE WEAKNESS,
HEADACHE, DIZZINESS). PROLONGED SKIN CONTACT MAY CAUSE SKIN IRRITATION
AND/OR DERMATITIS. SYMPTOMS OF SKIN IRRITATION MAY INCLUDE SKIN RASH,
BLISTERS, AND REDNESS. PROLONGED OR REPEATED SKIN CONTACT MAY CAUSE DRYNESS
OF THE SKIN.
SENSITIZATION: NO INFORMATION AVAILABLE.
MUTAGENIC EFFECTS:
MAY AFFECT GENETIC MATERIAL
EXPERIMENTS WITH BACTERIA AND/OR YEAST HAVE SHOWN MUTAGENIC EFFECTS
CARCINOGENIC EFFECTS: NOT CONSIDERED CARCINOGENIC.
FORMULA CAS NO IARC ACGIH - CARCINOGENS NTP
N-METHYL-2- 872-50-4 NOT LISTED NOT LISTED NOT LISTED
PYRROLIDINONE
FORMULA OSHA HCS - AUSTRALIA - AUSTRALIA -
CARCINOGENS NOTIFIABLE PROHIBITED
CARCINOGENIC CARCINOGENIC
SUBSTANCES SUBSTANCES
N-METHYL-2-PYRROLIDINONE NOT LISTED NOT LISTED NOT LISTED
ACGIH (AMERICAN CONFERENCE OF GOVERNMENTAL INDUSTRIAL HYGIENISTS)
IARC (INTERNATIONAL AGENCY FOR RESEARCH ON CANCER)
NTP (NATIONAL TOXICOLOGY PROGRAM)
OSHA (OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION OF THE US DEPARTMENT
OF LABOR)
REPRODUCTIVE TOXICITY: MAY DAMAGE FERTILITY OR THE UNBORN CHILD
REPRODUCTIVE EFFECTS: MAY IMPAIR FERTILITY
DEVELOPMENTAL EFFECTS:
MAY CAUSE ADVERSE DEVELOPMENTAL EFFECTS BASED ON ANIMAL DATA
TERATOGENIC EFFECTS:
MAY CAUSE BIRTH DEFECTS (TERATOGENIC EFFECTS) BASED ON ANIMAL TEST DATA
SHOWED TERATOGENIC EFFECTS IN ANIMAL EXPERIMENTS
SPECIFIC TARGET ORGAN TOXICITY:
STOT - SINGLE EXPOSURE: STOT - SINGLE EXPOSURE. RESPIRATORY SYSTEM.
STOT - REPEATED EXPOSURE: NO INFORMATION AVAILABLE.
TARGET ORGANS:
CENTRAL NERVOUS SYSTEM. SKIN. LIVER. KIDNEYS. BLOOD. RESPIRATORY SYSTEM.
SPLEEN. BONE MARROW. THYMUS.
| 12. ECOLOGICAL INFORMATION | |
ECOTOXICITY:
ECOTOXICITY EFFECTS: AQUATIC ENVIRONMENT.
N-METHYL-2-PYRROLIDINONE - 872-50-4:
ALGAE/AQUATIC PLANTS: 500 MG/L EC50 DESMODESMUS SUBSPICATUS 72 H
FISH:
1072 MG/L LC50 PIMEPHALES PROMELAS 96 H STATIC 1
1400 MG/L LC50 POECILIA RETICULATA 96 H STATIC 1
4000 MG/L LC50 LEUCISCUS IDUS 96 H STATIC 1
832 MG/L LC50 LEPOMIS MACROCHIRUS 96 H STATIC 1
CRUSTACEA: 4897 MG/L EC50 DAPHNIA MAGNA 48 H
PERSISTENCE AND DEGRADABILITY: READILY BIODEGRADABLE (90% )
BIOACCUMULATIVE POTENTIAL: NO INFORMATION AVAILABLE.
MOBILITY IN SOIL: NO INFORMATION AVAILABLE
OTHER ADVERSE EFFECTS: NO INFORMATION AVAILABLE.
| 13. DISPOSAL CONSIDERATIONS | |
DISPOSAL METHODS:
WASTE FROM RESIDUES / UNUSED PRODUCTS:
WASTE MUST BE DISPOSED OF IN ACCORDANCE WITH FEDERAL, STATE AND LOCAL
REGULATION.
CONTAMINATED PACKAGING:
EMPTY CONTAINERS SHOULD BE TAKEN FOR LOCAL RECYCLING, RECOVERY OR WASTE
DISPOSAL.
FORMULA CAS NO RCRA - F RCRA - K RCRA - P RCRA - U
SERIES SERIES SERIES SERIES
WASTES WASTES WASTES WASTES
N-METHYL-2- 872-50-4 NONE NONE NONE NONE
PYRROLIDINONE
| 14. TRANSPORT INFORMATION | |
DOT:
UN-NO: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
HAZARD CLASS: NO INFORMATION AVAILABLE
SUBSIDIARY CLASS: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
EMERGENCY RESPONSE GUIDE NUMBER: NO INFORMATION AVAILABLE
MARINE POLLUTANT: NO DATA AVAILABLE
DOT RQ (LBS): NO INFORMATION AVAILABLE
SPECIAL PROVISIONS: NO INFORMATION AVAILABLE
SYMBOL(S): NO INFORMATION AVAILABLE
DESCRIPTION: NO INFORMATION AVAILABLE
TDG (CANADA):
UN-NO: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
HAZARD CLASS: NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
MARINE POLLUTANT: NO INFORMATION AVAILABLE
DESCRIPTION: NO INFORMATION AVAILABLE
ADR:
UN NUMBER:
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
TRANSPORT HAZARD CLASS(ES): NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
IMDG:
UN-NO: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
HAZARD CLASS: NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
MARINE POLLUTANT: NO INFORMATION AVAILABLE
RID:
UN NUMBER: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
TRANSPORT HAZARD CLASS(ES): NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
ICAO (AIR):
UN-NO: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
HAZARD CLASS: NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
IATA:
UN NUMBER: NOT REGULATED
PROPER SHIPPING NAME: NO INFORMATION AVAILABLE
TRANSPORT HAZARD CLASS(ES): NO INFORMATION AVAILABLE
SUBSIDIARY RISK: NO INFORMATION AVAILABLE
PACKING GROUP: NO INFORMATION AVAILABLE
PRECAUTIONARY STATEMENTS - RESPONSE: IF EXPOSED OR CONCERNED
SPECIAL PROVISIONS: NO INFORMATION AVAILABLE
| 15. REGULATORY INFORMATION | |
INTERNATIONAL INVENTORIES:
FORMULA CAS NO U.S. TSCA KOREA KECL PHILIPPINES
(PICCS)
N-METHYL-2- 872-50-4 PRESENTACTIVE PRESENT PRESENT
PYRROLIDINONE KE-25324
FORMULA JAPAN ENCS CHINA IECSC AUSTRALIA AICS EINECS-NO.
N-METHYL-2- (5)-113 PRESENT PRESENT PRESENT
PYRROLIDINONE 212-828-1
U.S. REGULATIONS:
N-METHYL-2-PYRROLIDINONE:
MASSACHUSETTS RTK: PRESENT
NEW JERSEY RTK HAZARDOUS SUBSTANCE LIST: 3716
NEW JERSEY (EHS) LIST: 3716 500 LB TPQ
NEW JERSEY - DISCHARGE PREVENTION - LIST OF HAZARDOUS SUBSTANCES: PRESENT
PENNSYLVANIA RTK: PRESENT
CALIFORNIA PROP. 65: SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986.
CHEMICALS KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER:
THIS PRODUCT DOES NOT CONTAIN A CHEMICAL REQUIRING A WARNING UNDER
CALIFORNIA PROP. 65. (SEE TABLE BELOW)
CHEMICALS KNOWN TO THE STATE OF CALIFORNIA TO CAUSE REPRODUCTIVE TOXICITY:
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL KNOWN TO THE STATE OF CALIFORNIA TO CAUSE
BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM (SEE TABLE BELOW)
FORMULA CAS NO
N-METHYL-2-PYRROLIDINONE 872-50-4
FORMULA CARCINOGEN DEVELOPMENTAL MALE FEMALE
TOXICITY REPRODUCTIVE REPRODUCTIVE
TOXICITY TOXICITY
N-METHYL-2- NOT LISTED DEVELOPMENTAL NOT LISTED NOT LISTED
PYRROLIDINONE TOXICITY
CERCLA/SARA:
FORMULA CAS NO CERCLA - HAZARDOUS SUBSTANCES
AND THEIR REPORTABLE QUANTITIES
N-METHYL-2-PYRROLIDINONE 872-50-4 NONE
FORMULA SECTION 302 SECTION 302 SECTION 313 - SECTION 313 -
EXTREMELY EXTREMELY CHEMICAL REPORTING
HAZARDOUS HAZARDOUS CATEGORY DE MINIMIS
SUBSTANCES SUBSTANCES
AND TPQS AND RQS
N-METHYL-2- NONE NONE NONE 1.0% DE
PYRROLIDINONE MINIMIS
CONCENTRATION
U.S. TSCA:
FORMULA CAS NO TSCA SECTION TSCA 8(D) - HEALTH
5(A)2 - CHEMICALS AND SAFETY REPORTING
WITH SIGNIFICANT NEW
USE RULES (SNURS)
N-METHYL-2- 872-50-4 NOT APPLICABLE NOT APPLICABLE
PYRROLIDINONE
CANADA:
WHIMIS 2015 - GHS CLASSIFICATIONS:
WHMIS 2015 HAZARD CLASSIFICATION INFORMATION:
COMPONENT WHMIS 2015 HAZARD CLASSIFICATION
N-METHYL-2-PYRROLIDINONE FLAMMABLE LIQUIDS - CATEGORY 4:
872-50-4 (100) H227: COMBUSTIBLE LIQUID.
SERIOUS EYE DAMAGE/EYE IRRITATION - CATEGORY 2B:
H320: CAUSES EYE IRRITATION.
REPRODUCTIVE TOXICITY - CATEGORY 1:
H360: MAY DAMAGE FERTILITY OR THE UNBORN CHILD.
CANADA HAZARDOUS PRODUCTS REGULATION:
THIS PRODUCT HAS BEEN CLASSIFIED ACCORDING TO THE HAZARD CRITERIA OF THE
HPR (HAZARDOUS PRODUCTS REGULATION) AND THE SDS CONTAINS ALL OF THE
INFORMATION REQUIRED BY THE HPR
DSL/NDSL:
FORMULA CAS NO CANADA (DSL) CANADA (NDSL)
N-METHYL-2-PYRROLIDINONE 872-50-4 PRESENT NOT LISTED
FORMULA CAS NO CEPA SCHEDULE I - TOXIC SUBSTANCES
N-METHYL-2-PYRROLIDINONE 872-50-4 NOT LISTED
FORMULA CAS NO CEPA - 2010 GREENHOUSE GASES
SUBJECT TO MANDATORY REPORTING
N-METHYL-2-PYRROLIDINONE 872-50-4 NOT LISTED
EU CLASSIFICATION:
EU GHS - SV - CLP 1272/2008:
FORMULA CAS NO EU GHS - SV - CLP (1272/2008)
N-METHYL-2-PYRROLIDINONE 872-50-4
EU - CLP (1272/2008):
R-PHRASE(S):
R61: MAY CAUSE HARM TO THE UNBORN CHILD
R36/37/38: IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN
S - PHRASE(S):
S45:
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE IMMEDIATELY
(SHOW THE LABEL WHERE POSSIBLE)
S53: AVOID EXPOSURE - OBTAIN SPECIAL INSTRUCTIONS BEFORE USE
FORMULA CAS NO CLASSIFICATION CONCENTRATION SAFETY
LIMITS PHRASES
N-METHYL-2- 872-50-4 XI; R36/37/38 5%<=C: REPR.CAT.2; S53 S45
PYRROLIDINONE REPR.CAT.2; R61 R61
10%<=C: XI;
R36/37/38
THE PRODUCT IS CLASSIFIED IN ACCORDANCE WITH ANNEX VI TO DIRECTIVE
67/548/EEC:
INDICATION OF DANGER: XI - IRRITANT
| 16. OTHER INFORMATION | |
PREPARATION DATE: 06/03/2015
REVISION DATE: 11/30/2018
PREPARED BY: SONIA OWEN
DISCLAIMER:
ALL CHEMICALS MAY POSE UNKNOWN HAZARDS AND SHOULD BE USED WITH CAUTION.
THIS SAFETY DATA SHEET (SDS) APPLIES ONLY TO THE MATERIAL AS PACKAGED. IF
THIS PRODUCT IS COMBINED WITH OTHER MATERIALS, DETERIORATES, OR BECOMES
CONTAMINATED, IT MAY POSE HAZARDS NOT MENTIONED IN THIS SDS. THE PHYSICAL
PROPERTIES REPORTED IN THIS SDS ARE OBTAINED FROM THE LITERATURE AND DO NOT
CONSTITUTE PRODUCT SPECIFICATIONS. INFORMATION CONTAINED HEREIN DOES NOT
CONSTITUTE A WARRANTY, WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY,
MERCHANTABILITY OR FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. SPECTRUM
CHEMICALS & LABORATORY PRODUCTS, INC. ASSUMES NO RESPONSIBILITY FOR RESULTS
OBTAINED OR FOR INCIDENTAL OR CONSEQUENTIAL DAMAGES, INCLUDING LOST
PROFITS, ARISING FROM THE USE OF THESE DATA. NO WARRANTY AGAINST
INFRINGEMENT OF ANY PATENT, COPYRIGHT OR TRADEMARK IS MADE OR IMPLIED. IT
SHALL BE THE USER'S RESPONSIBILITY TO DEVELOP PROPER METHODS OF HANDLING
AND PERSONAL PROTECTION BASED ON THE ACTUAL CONDITIONS OF USE. WHILE THIS
SDS IS BASED ON TECHNICAL DATA JUDGED TO BE RELIABLE, SPECTRUM ASSUMES NO
RESPONSIBILITY FOR THE COMPLETENESS OR ACCURACY OF THE INFORMATION
CONTAINED HEREIN.