| Common Name: | ACETONITRILE |
| Manufacturer: | LABCHEM |
| SDS Revision Date: | 10/13/2020 |
| SDS Format: | No Format Specified |
| Item Number(s): | 8MWK1 |
| Manufacturer Model Number(s): |
SDS Table of Contents
Click the desired link below to jump directly to that section in the SDS.
LC
LABCHEM
PERFORMANCE THROUGH CHEMISTRY
ACETONITRILE
SAFETY DATA SHEET
ACCORDING TO FEDERAL REGISTER / VOL. 77, NO. 58 / MONDAY,
MARCH 26, 2012 / RULES AND REGULATIONS
ISSUE DATE: 06/22/2009
REVISION DATE: 10/13/2020
SUPERSEDES: 09/21/2016
VERSION: 1.3
| SECTION 1: IDENTIFICATION |  |
1.1. IDENTIFICATION:
PRODUCT FORM: SUBSTANCE
SUBSTANCE NAME: ACETONITRILE
CAS-NO.: 75-05-8
PRODUCT CODE: LC10460
FORMULA: C2H3N
SYNONYMS:
ACE / ACETIC ACID NITRILE / CYANOMETHANE / ETHANE NITRILE / ETHYL
NITRILE / METHANE CARBONITRILE / METHYL CYANIDE
1.2. RECOMMENDED USE AND RESTRICTIONS ON USE:
USE OF THE SUBSTANCE/MIXTURE:
LABORATORY CHEMICAL
SOLVENT
CHEMICAL RAW MATERIAL
PESTICIDE:
INTERMEDIATE PRODUCT
STABILIZER
CATALYST
1.3. SUPPLIER:
LABCHEM, INC.
1010 JACKSON'S POINTE CT.
ZELIENOPLE, PA 16063
USA
T: 412-826-5230
F: 724-473-0647
INFO@LABCHEM.COM - WWW.LABCHEM.COM
1.4. EMERGENCY TELEPHONE NUMBER:
EMERGENCY NUMBER:
CHEMTREC: 1-800-424-9300 OR +1-703-741-5970
| SECTION 2: HAZARD(S) IDENTIFICATION | |
2.1. CLASSIFICATION OF THE SUBSTANCE OR MIXTURE:
GHS US CLASSIFICATION:
FLAMMABLE LIQUIDS CATEGORY 2:
H225: HIGHLY FLAMMABLE LIQUID AND VAPOR
ACUTE TOXICITY (DERMAL) CATEGORY 3:
H311: TOXIC IN CONTACT WITH SKIN
FULL TEXT OF H STATEMENTS: SEE SECTION 16
2.2. GHS LABEL ELEMENTS, INCLUDING PRECAUTIONARY STATEMENTS:
GHS US LABELING:
HAZARD PICTOGRAMS (GHS US):
FLAME
SKULLS AND CROSSBONES
SIGNAL WORD (GHS US): DANGER
HAZARD STATEMENTS (GHS US):
H225: HIGHLY FLAMMABLE LIQUID AND VAPOR
H311: TOXIC IN CONTACT WITH SKIN
PRECAUTIONARY STATEMENTS (GHS US):
P210: KEEP AWAY FROM HEAT, SPARKS, OPEN FLAMES, HOT SURFACES. - NO SMOKING.
P233: KEEP CONTAINER TIGHTLY CLOSED.
P240: GROUND/BOND CONTAINER AND RECEIVING EQUIPMENT.
P241: USE EXPLOSION-PROOF ELECTRICAL, VENTILATING, LIGHTING EQUIPMENT.
P242: USE ONLY NON-SPARKING TOOLS.
P243: TAKE PRECAUTIONARY MEASURES AGAINST STATIC DISCHARGE.
P280:
WEAR PROTECTIVE GLOVES, PROTECTIVE CLOTHING, EYE PROTECTION, FACE
PROTECTION.
P302+P352:
IF ON SKIN: WASH WITH PLENTY OF SOAP AND WATER.
P303+P361+P353:
IF ON SKIN (OR HAIR):
REMOVE/TAKE OFF IMMEDIATELY ALL CONTAMINATED CLOTHING. RINSE SKIN WITH
WATER/SHOWER.
P312: CALL A POISON CENTER OR DOCTOR/PHYSICIAN IF YOU FEEL UNWELL.
P361: REMOVE/TAKE OFF IMMEDIATELY ALL CONTAMINATED CLOTHING
P363: WASH CONTAMINATED CLOTHING BEFORE REUSE.
P370+P378:
IN CASE OF FIRE:
USE CARBON DIOXIDE (CO2), POWDER, ALCOHOL-RESISTANT FOAM TO EXTINGUISH
P403+P235: STORE IN A WELL-VENTILATED PLACE. KEEP COOL.
P405: STORE LOCKED UP.
P501:
DISPOSE OF CONTENTS/CONTAINER TO COMPLY WITH LOCAL, STATE AND FEDERAL
REGULATIONS.
2.3. OTHER HAZARDS WHICH DO NOT RESULT IN CLASSIFICATION:
OTHER HAZARDS NOT CONTRIBUTING TO THE CLASSIFICATION: NONE.
2.4. UNKNOWN ACUTE TOXICITY (GHS US): NOT APPLICABLE
| SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS | |
3.1. SUBSTANCES:
SUBSTANCE TYPE: MONO-CONSTITUENT
NAME PRODUCT IDENTIFIER % GHS US CLASSIFICATION
ACETONITRILE (CAS-NO.): 75-05-8 100 FLAM. LIQ. 2, H225
(MAIN CONSTITUENT) ACUTE TOX. 3 (DERMAL), H311
FULL TEXT OF HAZARD CLASSES AND H-STATEMENTS: SEE SECTION 16
3.2. MIXTURES: NOT APPLICABLE
| SECTION 4: FIRST-AID MEASURES | |
4.1. DESCRIPTION OF FIRST AID MEASURES:
FIRST-AID MEASURES GENERAL:
CHECK THE VITAL FUNCTIONS. UNCONSCIOUS:
MAINTAIN ADEQUATE AIRWAY AND RESPIRATION.
RESPIRATORY ARREST: ARTIFICIAL RESPIRATION OR OXYGEN.
CARDIAC ARREST: PERFORM RESUSCITATION.
VICTIM CONSCIOUS WITH LABORED BREATHING: HALF-SEATED.
VICTIM IN SHOCK: ON HIS BACK WITH LEGS SLIGHTLY RAISED.
VOMITING:
PREVENT ASPHYXIA/ASPIRATION PNEUMONIA. PREVENT COOLING BY COVERING THE
VICTIM (NO WARMING UP). KEEP WATCHING THE VICTIM. GIVE PSYCHOLOGICAL AID.
KEEP THE VICTIM CALM, AVOID PHYSICAL STRAIN.
DEPENDING ON THE VICTIM'S CONDITION: DOCTOR/HOSPITAL.
FIRST-AID MEASURES AFTER INHALATION:
REMOVE THE VICTIM INTO FRESH AIR. DO NOT APPLY MOUTH-TO-MOUTH
RESUSCITATION.
RESPIRATORY PROBLEMS: CONSULT A DOCTOR/MEDICAL SERVICE.
FIRST-AID MEASURES AFTER SKIN CONTACT:
RINSE WITH WATER. SOAP MAY BE USED. DO NOT APPLY (CHEMICAL) NEUTRALIZING
AGENTS WITHOUT MEDICAL ADVICE. TAKE VICTIM TO A DOCTOR IF IRRITATION
PERSISTS.
FIRST-AID MEASURES AFTER EYE CONTACT:
RINSE IMMEDIATELY WITH PLENTY OF WATER. REMOVE CONTACT LENSES, IF PRESENT
AND EASY TO DO. CONTINUE RINSING. DO NOT APPLY (CHEMICAL) NEUTRALIZING
AGENTS WITHOUT MEDICAL ADVICE. TAKE VICTIM TO AN OPHTHALMOLOGIST IF
IRRITATION PERSISTS.
FIRST-AID MEASURES AFTER INGESTION:
RINSE MOUTH WITH WATER. DO NOT APPLY (CHEMICAL) NEUTRALIZING AGENTS WITHOUT
MEDICAL ADVICE. CALL POISON INFORMATION CENTRE (WWW.BIG.BE/ANTIGIF.HTM).
CONSULT A DOCTOR/MEDICAL SERVICE IF YOU FEEL UNWELL.
INGESTION OF LARGE QUANTITIES:
IMMEDIATELY TO HOSPITAL. TAKE THE CONTAINER/VOMIT TO THE DOCTOR/HOSPITAL.
DOCTOR: ADMINISTRATION OF CHEMICAL ANTIDOTE.
4.2. MOST IMPORTANT SYMPTOMS AND EFFECTS (ACUTE AND DELAYED):
POTENTIAL ADVERSE HUMAN HEALTH EFFECTS AND SYMPTOMS:
ODOUR THRESHOLD IS WELL ABOVE THE EXPOSURE LIMIT. ODOUR TOLERANCE MAY
DEVELOP. HARMFUL IF SWALLOWED. NOT IRRITANT TO SKIN. PRACTICALLY NON-TOXIC
IN CONTACT WITH SKIN (LD50 SKIN >2000 MG/KG). HARMFUL IN CONTACT WITH SKIN.
HARMFUL IF INHALED. CAUSES SERIOUS EYE IRRITATION.
SYMPTOMS/EFFECTS AFTER INHALATION:
EXPOSURE TO HIGH CONCENTRATIONS:
FOLLOWING SYMPTOMS MAY APPEAR LATER:
IRRITATION OF THE RESPIRATORY TRACT. IRRITATION OF THE NASAL MUCOUS
MEMBRANES. NAUSEA. HEADACHE. RESPIRATORY DIFFICULTIES. VOMITING. DIZZINESS.
DISTURBANCES OF CONSCIOUSNESS. FEELING OF WEAKNESS. RISK OF LUNG EDEMA.
CHANGE IN THE HAEMOGRAMME/BLOOD COMPOSITION. CRAMPS/UNCONTROLLED MUSCULAR
CONTRACTIONS. MENTAL CONFUSION. DISTURBANCES OF HEART RATE. INCREASED
SALIVATION.
SYMPTOMS/EFFECTS AFTER SKIN CONTACT:
FOLLOWING SYMPTOMS MAY APPEAR LATER:
SYMPTOMS SIMILAR TO THOSE LISTED UNDER INHALATION.
SYMPTOMS/EFFECTS AFTER EYE CONTACT: IRRITATION OF THE EYE TISSUE.
SYMPTOMS/EFFECTS AFTER INGESTION:
FOLLOWING SYMPTOMS MAY APPEAR LATER:
RISK OF ASPIRATION PNEUMONIA. SYMPTOMS SIMILAR TO THOSE LISTED UNDER
INHALATION.
CHRONIC SYMPTOMS:
SIMILAR PRODUCTS CAUSE FOLLOWING SYMPTOMS:
ON CONTINUOUS/REPEATED EXPOSURE/CONTACT:
HEADACHE. DIZZINESS. FEELING OF WEAKNESS. GASTROINTESTINAL COMPLAINTS.
LOSS OF APPETITE. RUNNY NOSE. LOSS OF WEIGHT. NO SPECIFIC INFORMATION
AVAILABLE.
4.3. IMMEDIATE MEDICAL ATTENTION AND SPECIAL TREATMENT, IF NECESSARY:
NO ADDITIONAL INFORMATION AVAILABLE
| SECTION 5: FIRE-FIGHTING MEASURES | |
5.1. SUITABLE (AND UNSUITABLE) EXTINGUISHING MEDIA:
SUITABLE EXTINGUISHING MEDIA:
QUICK-ACTING ABC POWDER EXTINGUISHER. QUICK-ACTING BC POWDER EXTINGUISHER.
QUICK-ACTING CLASS B FOAM EXTINGUISHER. QUICK-ACTING CO2 EXTINGUISHER.
CLASS B FOAM (ALCOHOL-RESISTANT). WATER SPRAY IF PUDDLE CANNOT EXPAND.
UNSUITABLE EXTINGUISHING MEDIA:
WATER (QUICK-ACTING EXTINGUISHER, REEL); RISK OF PUDDLE EXPANSION. WATER;
RISK OF PUDDLE EXPANSION.
5.2. SPECIFIC HAZARDS ARISING FROM THE CHEMICAL:
FIRE HAZARD:
DIRECT FIRE HAZARD. HIGHLY FLAMMABLE LIQUID AND VAPOUR. GAS/VAPOR FLAMMABLE
WITH AIR WITHIN EXPLOSION LIMITS. INDIRECT FIRE HAZARD.
MAY BUILD UP ELECTROSTATIC CHARGES:
RISK OF IGNITION. MAY BE IGNITED BY SPARKS. GAS/VAPOR SPREADS AT FLOOR
LEVEL: IGNITION HAZARD.
REACTIONS INVOLVING A FIRE HAZARD: SEE "REACTIVITY HAZARD".
EXPLOSION HAZARD:
DIRECT EXPLOSION HAZARD. GAS/VAPOUR EXPLOSIVE WITH AIR WITHIN EXPLOSION
LIMITS. INDIRECT EXPLOSION HAZARD. MAY BE IGNITED BY SPARKS.
REACTIONS WITH EXPLOSION HAZARDS: SEE "REACTIVITY HAZARD".
HAZARDOUS DECOMPOSITION PRODUCTS IN CASE OF FIRE:
ON BURNING:
RELEASE OF TOXIC AND CORROSIVE GASES/VAPOURS (NITROUS VAPOURS, CARBON
MONOXIDE - CARBON DIOXIDE).
5.3. SPECIAL PROTECTIVE EQUIPMENT AND PRECAUTIONS FOR FIRE-FIGHTERS:
FIREFIGHTING INSTRUCTIONS:
COOL TANKS/DRUMS WITH WATER SPRAY/REMOVE THEM INTO SAFETY. DO NOT MOVE
THE LOAD IF EXPOSED TO HEAT. DILUTE TOXIC GASES WITH WATER SPRAY. TAKE
ACCOUNT OF TOXIC/CORROSIVE PRECIPITATION WATER.
PROTECTION DURING FIREFIGHTING:
HEAT/FIRE EXPOSURE: COMPRESSED AIR APPARATUS (EN 136 + EN 137).
| SECTION 6: ACCIDENTAL RELEASE MEASURES | |
6.1. PERSONAL PRECAUTIONS, PROTECTIVE EQUIPMENT AND EMERGENCY PROCEDURES:
6.1.1. FOR NON-EMERGENCY PERSONNEL:
PROTECTIVE EQUIPMENT:
GLOVES (EN 374). PROTECTIVE GOGGLES (EN 166). HEAD/NECK PROTECTION.
PROTECTIVE CLOTHING (EN 14605 OR EN 13034).
LARGE SPILLS/IN ENCLOSED SPACES: GAS-TIGHT SUIT (EN 943).
LARGE SPILLS/IN ENCLOSED SPACES:
COMPRESSED AIR APPARATUS (EN 136 + EN 137).
EMERGENCY PROCEDURES:
KEEP UPWIND. MARK THE DANGER AREA. CONSIDER EVACUATION. SEAL OFF LOW-LYING
AREAS. CLOSE DOORS AND WINDOWS OF ADJACENT PREMISES. STOP ENGINES AND NO
SMOKING. NO NAKED FLAMES OR SPARKS. SPARK- AND EXPLOSION-PROOF APPLIANCES
AND LIGHTING EQUIPMENT. KEEP CONTAINERS CLOSED. WASH CONTAMINATED CLOTHES.
6.1.2. FOR EMERGENCY RESPONDERS:
PROTECTIVE EQUIPMENT: EQUIP CLEANUP CREW WITH PROPER PROTECTION.
EMERGENCY PROCEDURES: VENTILATE AREA. STOP LEAK IF SAFE TO DO SO.
6.2. ENVIRONMENTAL PRECAUTIONS: PREVENT SPREADING IN SEWERS.
6.3. METHODS AND MATERIAL FOR CONTAINMENT AND CLEANING UP:
FOR CONTAINMENT:
CONTAIN RELEASED SUBSTANCE, PUMP INTO SUITABLE CONTAINERS. PLUG THE LEAK,
CUT OFF THE SUPPLY. DAM UP THE LIQUID SPILL. TRY TO REDUCE EVAPORATION.
MEASURE THE CONCENTRATION OF THE EXPLOSIVE GAS-AIR MIXTURE. DILUTE/DISPERSE
COMBUSTIBLE GAS/VAPOUR WITH WATER CURTAIN. PROVIDE EQUIPMENT/RECEPTACLES
WITH EARTHING. DO NOT USE COMPRESSED AIR FOR PUMPING OVER SPILLS.
METHODS FOR CLEANING UP:
TAKE UP LIQUID SPILL INTO A NON COMBUSTIBLE MATERIAL E.G.:
SAND, EARTH, VERMICULITE. SCOOP ABSORBED SUBSTANCE INTO CLOSING CONTAINERS.
CAREFULLY COLLECT THE SPILL/LEFTOVERS. DAMAGED/COOLED TANKS MUST BE
EMPTIED. DO NOT USE COMPRESSED AIR FOR PUMPING OVER SPILLS. CLEAN
CONTAMINATED SURFACES WITH AN EXCESS OF WATER. TAKE COLLECTED SPILL TO
MANUFACTURER/COMPETENT AUTHORITY. WASH CLOTHING AND EQUIPMENT AFTER
HANDLING.
6.4. REFERENCE TO OTHER SECTIONS: NO ADDITIONAL INFORMATION AVAILABLE
| SECTION 7: HANDLING AND STORAGE | |
7.1. PRECAUTIONS FOR SAFE HANDLING:
PRECAUTIONS FOR SAFE HANDLING:
USE SPARK-/EXPLOSIONPROOF APPLIANCES AND LIGHTING SYSTEM. TAKE PRECAUTIONS
AGAINST ELECTROSTATIC CHARGES. KEEP AWAY FROM NAKED FLAMES/HEAT. KEEP AWAY
FROM IGNITION SOURCES/SPARKS. MEASURE THE CONCENTRATION IN THE AIR
REGULARLY. WORK UNDER LOCAL EXHAUST/VENTILATION. COMPLY WITH THE LEGAL
REQUIREMENTS. REMOVE CONTAMINATED CLOTHING IMMEDIATELY. CLEAN CONTAMINATED
CLOTHING. HANDLE UNCLEANED EMPTY CONTAINERS AS FULL ONES. THOROUGHLY
CLEAN/DRY THE INSTALLATION BEFORE USE. DO NOT DISCHARGE THE WASTE INTO THE
DRAIN. DO NOT USE COMPRESSED AIR FOR PUMPING OVER. AVOID CONTACT OF
SUBSTANCE WITH WATER. KEEP CONTAINER TIGHTLY CLOSED.
HYGIENE MEASURES:
DO NOT EAT, DRINK OR SMOKE WHEN USING THIS PRODUCT. WASH HANDS AND OTHER
EXPOSED AREAS WITH MILD SOAP AND WATER BEFORE EATING, DRINKING OR SMOKING
AND WHEN LEAVING WORK. WASH CONTAMINATED CLOTHING BEFORE REUSE.
7.2. CONDITIONS FOR SAFE STORAGE, INCLUDING ANY INCOMPATIBILITIES:
INCOMPATIBLE PRODUCTS: OXIDIZING AGENT. SILVER NITRATE.
INCOMPATIBLE MATERIALS: HEAT SOURCES. SOURCES OF IGNITION. DIRECT SUNLIGHT.
STORAGE TEMPERATURE: -20 DEG. C
HEAT-IGNITION:
KEEP SUBSTANCE AWAY FROM: HEAT SOURCES. IGNITION SOURCES.
PROHIBITIONS ON MIXED STORAGE:
KEEP SUBSTANCE AWAY FROM:
OXIDIZING AGENTS. REDUCING AGENTS. STRONG ACIDS. (STRONG) BASES.
WATER/MOISTURE.
STORAGE AREA:
STORE IN A DRY AREA. VENTILATION AT FLOOR LEVEL. FIREPROOF STOREROOM.
PROVIDE FOR A TUB TO COLLECT SPILLS. PROVIDE THE TANK WITH EARTHING.
STORE AT AMBIENT TEMPERATURE. KEEP OUT OF DIRECT SUNLIGHT. MEET THE
LEGAL REQUIREMENTS.
SPECIAL RULES ON PACKAGING:
SPECIAL REQUIREMENTS:
HERMETICAL. DRY. CLEAN. CORRECTLY LABELLED. MEET THE LEGAL REQUIREMENTS.
SECURE FRAGILE PACKAGINGS IN SOLID CONTAINERS.
PACKAGING MATERIALS:
SUITABLE MATERIAL: STAINLESS STEEL. ALUMINIUM. IRON. POLYETHYLENE. GLASS.
MATERIAL TO AVOID: COPPER. PLASTICS.
| SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION | |
8.1. CONTROL PARAMETERS:
ACETONITRILE (75-05-8):
USA - ACGIH - OCCUPATIONAL EXPOSURE LIMITS:
LOCAL NAME: ACETONITRILE
ACGIH TWA (MG/M3): 34 MG/M3
ACGIH TWA (PPM): 20 PPM
REMARK (ACGIH):
TLV(R*) BASIS: LRT IRR.
NOTATIONS: SKIN; A4 (NOT CLASSIFIABLE AS A HUMAN CARCINOGEN)
REGULATORY REFERENCE: ACGIH 2020
USA - OSHA - OCCUPATIONAL EXPOSURE LIMITS:
LOCAL NAME: ACETONITRILE
OSHA PEL (TWA) (MG/M3): 70 MG/M3
OSHA PEL (TWA) (PPM): 40 PPM
REGULATORY REFERENCE (US-OSHA): OSHA ANNOTATED TABLE Z-1
USA - IDLH - OCCUPATIONAL EXPOSURE LIMITS:
US IDLH (PPM): 500 PPM
USA - NIOSH - OCCUPATIONAL EXPOSURE LIMITS:
NIOSH REL (TWA) (MG/M3): 34 MG/M3
NIOSH REL (TWA) [PPM]: 20 PPM
8.2. APPROPRIATE ENGINEERING CONTROLS:
APPROPRIATE ENGINEERING CONTROLS:
ENSURE ADEQUATE VENTILATION. EMERGENCY EYE WASH FOUNTAINS AND SAFETY
SHOWERS SHOULD BE AVAILABLE IN THE IMMEDIATE VICINITY OF ANY POTENTIAL
EXPOSURE.
8.3. INDIVIDUAL PROTECTION MEASURES/PERSONAL PROTECTIVE EQUIPMENT:
PERSONAL PROTECTIVE EQUIPMENT:
SAFETY GLASSES. GLOVES. HIGH GAS/VAPOR CONCENTRATION:
GAS MASK WITH FILTER TYPE A. CHEMICAL RESISTANT APRON.
MATERIALS FOR PROTECTIVE CLOTHING:
GIVE GOOD RESISTANCE:
BUTYL RUBBER. CHLORINATED POLYETHYLENE. TETRAFLUOROETHYLENE. NEOPRENE/BUTYL
RUBBER. NEOPRENE/NATURAL RUBBER. POLYETHYLENE/ETHYLENEVINYLALCOHOL.
GIVE LESS RESISTANCE: PVA.
GIVE POOR RESISTANCE:
NITRILE RUBBER. POLYETHYLENE. NATURAL RUBBER. NEOPRENE. PVC. VITON
HAND PROTECTION: PROTECTIVE GLOVES AGAINST CHEMICALS (EN 374)
EYE PROTECTION: PROTECTIVE GOGGLES (EN 166)
SKIN AND BODY PROTECTION:
PROTECTIVE CLOTHING (EN 14605 OR EN 13034). HEAD/NECK PROTECTION
RESPIRATORY PROTECTION:
FULL FACE MASK WITH FILTER TYPE A AT CONC. IN AIR > EXPOSURE LIMIT
PERSONAL PROTECTIVE EQUIPMENT SYMBOL(S):
CHEMICAL GOGGLES
GLOVES
FULL-FACE RESPIRATOR
APRON
| SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES | |
9.1. INFORMATION ON BASIC PHYSICAL AND CHEMICAL PROPERTIES:
PHYSICAL STATE: LIQUID
APPEARANCE: LIQUID.
COLOR: COLOURLESS
ODOR: SWEET ODOUR AROMATIC ODOUR ETHER-LIKE ODOUR
ODOR THRESHOLD: NO DATA AVAILABLE
PH: NO DATA AVAILABLE
MELTING POINT: -46 DEG. C
FREEZING POINT: NO DATA AVAILABLE
BOILING POINT: 82 DEG. C (1013 HPA)
CRITICAL TEMPERATURE: 275 DEG. C
CRITICAL PRESSURE: 48320 HPA
FLASH POINT: 6 DEG. C (OPEN CUP)
RELATIVE EVAPORATION RATE (BUTYL ACETATE=1): 5.8
FLAMMABILITY (SOLID, GAS): NO DATA AVAILABLE
VAPOR PRESSURE: 94.61 HPA (20 DEG. C)
RELATIVE VAPOR DENSITY AT 20 DEG. C: 1.42
RELATIVE DENSITY: 0.79 (20 DEG. C)
RELATIVE DENSITY OF SATURATED GAS/AIR MIXTURE: 1.04
SPECIFIC GRAVITY / DENSITY: 787 KG/M3
MOLECULAR MASS: 41.05 G/MOL
SOLUBILITY:
SOLUBLE IN WATER. SOLUBLE IN ETHANOL. SOLUBLE IN ETHER. SOLUBLE IN ACETONE.
SOLUBLE IN CHLOROFORM. SOLUBLE IN METHYLACETATE. SOLUBLE IN DICHLOROETHANE.
SOLUBLE IN TETRACHLOROMETHANE. SOLUBLE IN TETRACHLOROETHENE. SOLUBLE IN
METHANOL. SOLUBLE IN ETHYLACETATE. SOLUBLE IN OILS/FATS.
WATER: 25 DEG. C, COMPLETE
ETHANOL: COMPLETE
ETHER: COMPLETE
ACETONE: COMPLETE
LOG POW:
-0.54 (WEIGHT OF EVIDENCE APPROACH, EQUIVALENT OR SIMILAR TO OECD 107,
25 DEG. C)
AUTO-IGNITION TEMPERATURE: 524 DEG. C
DECOMPOSITION TEMPERATURE: >120 DEG. C
VISCOSITY, KINEMATIC: 3.8 MM2/S
VISCOSITY, DYNAMIC: 3 MPA.S (40 DEG. C)
EXPLOSION LIMITS:
3 - 16 VOL %
50 - 274 G/M3
LOWER EXPLOSIVE LIMIT (LEL): 3 VOL %
UPPER EXPLOSIVE LIMIT (UEL): 16 VOL %
EXPLOSIVE PROPERTIES: NO DATA AVAILABLE
OXIDIZING PROPERTIES: NO DATA AVAILABLE
9.2. OTHER INFORMATION:
SPECIFIC CONDUCTIVITY: 60000 PS/M
SATURATION CONCENTRATION: 163 G/M3
VOC CONTENT: 100%
OTHER PROPERTIES:
GAS/VAPOUR HEAVIER THAN AIR AT 20 DEG. C. CLEAR. VOLATILE. NEUTRAL
REACTION. MAY GENERATE ELECTROSTATIC CHARGES.
| SECTION 10: STABILITY AND REACTIVITY | |
10.1. REACTIVITY:
REACTS VIOLENTLY WITH (STRONG) OXIDIZERS:
(INCREASED) RISK OF FIRE/EXPLOSION. REACTS VIOLENTLY WITH (STRONG)
REDUCERS.
10.2. CHEMICAL STABILITY: UNSTABLE ON EXPOSURE TO MOISTURE.
10.3. POSSIBILITY OF HAZARDOUS REACTIONS:
NO ADDITIONAL INFORMATION AVAILABLE
10.4. CONDITIONS TO AVOID: HIGH TEMPERATURE. OPEN FLAME. SPARKS.
10.5. INCOMPATIBLE MATERIALS:
OXIDIZING AGENT. STRONG REDUCING AGENTS. STRONG ACIDS.
10.6. HAZARDOUS DECOMPOSITION PRODUCTS:
CARBON DIOXIDE. CARBON MONOXIDE. NITROGEN OXIDES. CYANIDES.
| SECTION 11: TOXICOLOGICAL INFORMATION | |
11.1. INFORMATION ON TOXICOLOGICAL EFFECTS:
ACUTE TOXICITY (ORAL): NOT CLASSIFIED
ACUTE TOXICITY (DERMAL): TOXIC IN CONTACT WITH SKIN.
ACUTE TOXICITY (INHALATION): NOT CLASSIFIED
ACETONITRILE (75-05-8):
LD50 DERMAL RABBIT:
>2000 MG/KG BODY WEIGHT (EQUIVALENT OR SIMILAR TO OECD 402, 24 H, RABBIT,
MALE / FEMALE, EXPERIMENTAL VALUE, DERMAL, 14 DAY(S))
ATE US (DERMAL): 980 MG/KG BODY WEIGHT
ATE US (DUST, MIST): 27 MG/L/4H
SKIN CORROSION/IRRITATION: NOT CLASSIFIED
SERIOUS EYE DAMAGE/IRRITATION: NOT CLASSIFIED
RESPIRATORY OR SKIN SENSITIZATION: NOT CLASSIFIED
GERM CELL MUTAGENICITY: NOT CLASSIFIED
CARCINOGENICITY: NOT CLASSIFIED
REPRODUCTIVE TOXICITY: NOT CLASSIFIED
STOT-SINGLE EXPOSURE: NOT CLASSIFIED
STOT-REPEATED EXPOSURE: NOT CLASSIFIED
ASPIRATION HAZARD: NOT CLASSIFIED
VISCOSITY, KINEMATIC: 3.8 MM2/S
LIKELY ROUTES OF EXPOSURE: INHALATION. SKIN AND EYE CONTACT.
POTENTIAL ADVERSE HUMAN HEALTH EFFECTS AND SYMPTOMS:
ODOUR THRESHOLD IS WELL ABOVE THE EXPOSURE LIMIT. ODOUR TOLERANCE MAY
DEVELOP. HARMFUL IF SWALLOWED. NOT IRRITANT TO SKIN. PRACTICALLY NON-TOXIC
IN CONTACT WITH SKIN (LD50 SKIN >2000 MG/KG). HARMFUL IN CONTACT WITH SKIN.
HARMFUL IF INHALED. CAUSES SERIOUS EYE IRRITATION.
SYMPTOMS/EFFECTS AFTER INHALATION:
EXPOSURE TO HIGH CONCENTRATIONS:
FOLLOWING SYMPTOMS MAY APPEAR LATER:
IRRITATION OF THE RESPIRATORY TRACT. IRRITATION OF THE NASAL MUCOUS
MEMBRANES. NAUSEA. HEADACHE. RESPIRATORY DIFFICULTIES. VOMITING. DIZZINESS.
DISTURBANCES OF CONSCIOUSNESS. FEELING OF WEAKNESS. RISK OF LUNG EDEMA.
CHANGE IN THE HAEMOGRAMME/BLOOD COMPOSITION. CRAMPS/UNCONTROLLED MUSCULAR
CONTRACTIONS. MENTAL CONFUSION. DISTURBANCES OF HEART RATE. INCREASED
SALIVATION.
SYMPTOMS/EFFECTS AFTER SKIN CONTACT:
FOLLOWING SYMPTOMS MAY APPEAR LATER:
SYMPTOMS SIMILAR TO THOSE LISTED UNDER INHALATION.
SYMPTOMS/EFFECTS AFTER EYE CONTACT: IRRITATION OF THE EYE TISSUE.
SYMPTOMS/EFFECTS AFTER INGESTION:
FOLLOWING SYMPTOMS MAY APPEAR LATER:
RISK OF ASPIRATION PNEUMONIA. SYMPTOMS SIMILAR TO THOSE LISTED UNDER
INHALATION.
CHRONIC SYMPTOMS:
SIMILAR PRODUCTS CAUSE FOLLOWING SYMPTOMS:
ON CONTINUOUS/REPEATED EXPOSURE/CONTACT:
HEADACHE. DIZZINESS. FEELING OF WEAKNESS. GASTROINTESTINAL COMPLAINTS.
LOSS OF APPETITE. RUNNY NOSE. LOSS OF WEIGHT. NO SPECIFIC INFORMATION
AVAILABLE.
| SECTION 12: ECOLOGICAL INFORMATION | |
12.1. TOXICITY:
ECOLOGY - GENERAL:
NOT CLASSIFIED AS DANGEROUS FOR THE ENVIRONMENT ACCORDING TO THE CRITERIA
OF REGULATION (EC) NO 1272/2008.
ECOLOGY - AIR:
NOT INCLUDED IN THE LIST OF SUBSTANCES WHICH MAY CONTRIBUTE TO THE
GREENHOUSE EFFECT (IPCC). NOT INCLUDED IN THE LIST OF FLUORINATED
GREENHOUSE GASES (REGULATION (EU) NO 517/2014). NOT CLASSIFIED AS
DANGEROUS FOR THE OZONE LAYER (REGULATION (EC) NO 1005/2009).
ECOLOGY - WATER:
NOT HARMFUL TO CRUSTACEA. NOT HARMFUL TO FISHES. GROUNDWATER POLLUTANT.
NO INHIBITION OF ACTIVATED SLUDGE. NOT HARMFUL TO ALGAE. NOT HARMFUL TO
BACTERIA.
ACETONITRILE (75-05-8):
LC50 FISH 1:
1640 MG/L (96 H, PIMEPHALES PROMELAS, FLOW-THROUGH SYSTEM, FRESH WATER,
EXPERIMENTAL VALUE, SOFT WATER)
EC50 DAPHNIA 1:
>1000 MG/L (OECD 202: DAPHNIA SP. ACUTE IMMOBILISATION TEST, 48 H, DAPHNIA
MAGNA, SEMISTATIC SYSTEM, FRESH WATER, EXPERIMENTAL VALUE, GLP)
ERC50 (ALGAE):
9696 MG/L (ISO 10253, 72 H, PHAEODACTYLUM, STATIC SYSTEM, SALT WATER,
EXPERIMENTAL VALUE, GLP)
12.2. PERSISTENCE AND DEGRADABILITY:
ACETONITRILE (75-05-8):
PERSISTENCE AND DEGRADABILITY: READILY BIODEGRADABLE IN WATER.
BIOCHEMICAL OXYGEN DEMAND (BOD): 0.17 G O2/G SUBSTANCE
THOD: 3.12 G O2/G SUBSTANCE
12.3. BIOACCUMULATIVE POTENTIAL:
ACETONITRILE (75-05-8):
LOG POW:
-0.54 (WEIGHT OF EVIDENCE APPROACH, EQUIVALENT OR SIMILAR TO OECD 107,
25 DEG. C)
BIOACCUMULATIVE POTENTIAL: NOT BIOACCUMULATIVE.
12.4. MOBILITY IN SOIL:
ACETONITRILE (75-05-8):
SURFACE TENSION: 0.029 N/M (20 DEG. C)
LOG KOC: 0.65 (LOG KOC, CALCULATED VALUE)
ECOLOGY - SOIL: HIGHLY MOBILE IN SOIL.
12.5. OTHER ADVERSE EFFECTS: NO ADDITIONAL INFORMATION AVAILABLE
| SECTION 13: DISPOSAL CONSIDERATIONS | |
13.1. DISPOSAL METHODS:
WASTE DISPOSAL RECOMMENDATIONS:
DO NOT DISCHARGE INTO DRAINS OR THE ENVIRONMENT. DISPOSE OF AT AUTHORIZED
WASTE COLLECTION POINT. REMOVE WASTE IN ACCORDANCE WITH LOCAL AND/OR
NATIONAL REGULATIONS. HAZARDOUS WASTE SHALL NOT BE MIXED TOGETHER WITH
OTHER WASTE. DIFFERENT TYPES OF HAZARDOUS WASTE SHALL NOT BE MIXED TOGETHER
IF THIS MAY ENTAIL A RISK OF POLLUTION OR CREATE PROBLEMS FOR THE FURTHER
MANAGEMENT OF THE WASTE. HAZARDOUS WASTE SHALL BE MANAGED RESPONSIBLY. ALL
ENTITIES THAT STORE, TRANSPORT OR HANDLE HAZARDOUS WASTE SHALL TAKE THE
NECESSARY MEASURES TO PREVENT RISKS OF POLLUTION OR DAMAGE TO PEOPLE OR
ANIMALS.
ADDITIONAL INFORMATION:
HAZARDOUS WASTE ACCORDING TO DIRECTIVE 2008/98/EC, AS AMENDED BY REGULATION
(EU) NO 1357/2014 AND REGULATION (EU) NO 2017/997.
| SECTION 14: TRANSPORT INFORMATION | |
DEPARTMENT OF TRANSPORTATION (DOT):
IN ACCORDANCE WITH DOT:
TRANSPORT DOCUMENT DESCRIPTION: UN1648 ACETONITRILE, 3, II
UN-NO.(DOT): UN1648
PROPER SHIPPING NAME (DOT): ACETONITRILE
TRANSPORT HAZARD CLASS(ES) (DOT):
3 - CLASS 3 - FLAMMABLE AND COMBUSTIBLE LIQUID 49 CFR 173.120
PACKING GROUP (DOT): II - MEDIUM DANGER
HAZARD LABELS (DOT): 3 - FLAMMABLE LIQUID
DOT PACKAGING NON BULK (49 CFR 173.XXX): 202
DOT PACKAGING BULK (49 CFR 173.XXX): 242
DOT SPECIAL PROVISIONS (49 CFR 172.102):
IB2 - AUTHORIZED IBCS:
METAL (31A, 31B AND 31N); RIGID PLASTICS (31H1 AND 31H2); COMPOSITE
(31HZ1).
ADDITIONAL REQUIREMENT:
ONLY LIQUIDS WITH A VAPOR PRESSURE LESS THAN OR EQUAL TO 110 KPA AT 50 C
(1.1 BAR AT 122 F), OR 130 KPA AT 55 C (1.3 BAR AT 131 F) ARE AUTHORIZED.
T7 - 4 178.274(D)(2) NORMAL............. 178.275(D)(3)
TP2 - A. THE MAXIMUM DEGREE OF FILLING MUST NOT EXCEED THE DEGREE OF
FILLING DETERMINED BY THE FOLLOWING:
(IMAGE) WHERE:
TR IS THE MAXIMUM MEAN BULK TEMPERATURE DURING TRANSPORT, TF IS THE
TEMPERATURE IN DEGREES CELSIUS OF THE LIQUID DURING FILLING, AND A IS THE
MEAN COEFFICIENT OF CUBICAL EXPANSION OF THE LIQUID BETWEEN THE MEAN
TEMPERATURE OF THE LIQUID DURING FILLING (TF) AND THE MAXIMUM MEAN BULK
TEMPERATURE DURING TRANSPORTATION (TR) BOTH IN DEGREES CELSIUS.
B. FOR LIQUIDS TRANSPORTED UNDER AMBIENT CONDITIONS MAY BE CALCULATED USING
THE FORMULA:
(IMAGE) WHERE:
D15 AND D50 ARE THE DENSITIES (IN UNITS OF MASS PER UNIT VOLUME) OF THE
LIQUID AT 15 C (59 F) AND 50 C (122 F), RESPECTIVELY.
DOT PACKAGING EXCEPTIONS (49 CFR 173.XXX): 150
DOT QUANTITY LIMITATIONS PASSENGER AIRCRAFT/RAIL (49 CFR 173.27): 5L
DOT QUANTITY LIMITATIONS CARGO AIRCRAFT ONLY (49 CFR 175.75): 60 L
DOT VESSEL STOWAGE LOCATION:
B - (I) THE MATERIAL MAY BE STOWED "ON DECK" OR "UNDER DECK" ON A CARGO
VESSEL AND ON A PASSENGER VESSEL CARRYING A NUMBER OF PASSENGERS LIMITED
TO NOT MORE THAN THE LARGER OF 25 PASSENGERS, OR ONE PASSENGER PER EACH
3 M OF OVERALL VESSEL LENGTH; AND (II) "ON DECK ONLY" ON PASSENGER VESSELS
IN WHICH THE NUMBER OF PASSENGERS SPECIFIED IN PARAGRAPH (K)(2)(I) OF THIS
SECTION IS EXCEEDED.
DOT VESSEL STOWAGE OTHER: 40 - STOW "CLEAR OF LIVING QUARTERS"
OTHER INFORMATION: NO SUPPLEMENTARY INFORMATION AVAILABLE.
| SECTION 15: REGULATORY INFORMATION | |
15.1. US FEDERAL REGULATIONS:
ACETONITRILE (75-05-8):
LISTED ON THE UNITED STATES TSCA (TOXIC SUBSTANCES CONTROL ACT) INVENTORY
RQ (REPORTABLE QUANTITY, SECTION 304 OF EPA'S LIST OF LISTS): 5000 LB
SARA SECTION 311/312 HAZARD CLASSES:
PHYSICAL HAZARD: FLAMMABLE (GASES, AEROSOLS, LIQUIDS, OR SOLIDS)
HEALTH HAZARD: ACUTE TOXICITY (ANY ROUTE OF EXPOSURE)
ALL COMPONENTS OF THIS PRODUCT ARE LISTED, OR EXCLUDED FROM LISTING, ON
THE UNITED STATES ENVIRONMENTAL PROTECTION AGENCY TOXIC SUBSTANCES CONTROL
ACT (TSCA) INVENTORY
15.2. INTERNATIONAL REGULATIONS:
CANADA:
ACETONITRILE (75-05-8):
LISTED ON THE CANADIAN DSL (DOMESTIC SUBSTANCES LIST)
EU-REGULATIONS: NO ADDITIONAL INFORMATION AVAILABLE
NATIONAL REGULATIONS: NO ADDITIONAL INFORMATION AVAILABLE
15.3. US STATE REGULATIONS:
CALIFORNIA PROPOSITION 65:
THIS PRODUCT DOES NOT CONTAIN ANY SUBSTANCES KNOWN TO THE STATE OF
CALIFORNIA TO CAUSE CANCER, DEVELOPMENTAL AND/OR REPRODUCTIVE HARM
| SECTION 16: OTHER INFORMATION | |
ACCORDING TO FEDERAL REGISTER / VOL. 77, NO. 58 / MONDAY,
MARCH 26, 2012 / RULES AND REGULATIONS
REVISION DATE: 10/13/2020
FULL TEXT OF H-PHRASES: SEE SECTION 16
H225: HIGHLY FLAMMABLE LIQUID AND VAPOR
H311: TOXIC IN CONTACT WITH SKIN
NFPA HEALTH HAZARD 2 - MATERIALS THAT, UNDER EMERGENCY CONDITIONS, CAN
CAUSE TEMPORARY INCAPACITATION OR RESIDUAL INJURY.
NFPA FIRE HAZARD 3 - LIQUIDS AND SOLIDS (INCLUDING FINELY DIVIDED
SUSPENDED SOLIDS) THAT CAN BE IGNITED UNDER ALMOST
ALL AMBIENT TEMPERATURE CONDITIONS.
NFPA REACTIVITY 0 - MATERIAL THAT IN THEMSELVES ARE NORMALLY STABLE,
EVEN UNDER FIRE CONDITIONS.
HAZARD RATING:
HEALTH 2 MODERATE HAZARD - TEMPORARY OR MINOR INJURY MAY OCCUR
FLAMMABILITY 3 SERIOUS HAZARD - MATERIALS CAPABLE OF IGNITION UNDER
ALMOST ALL NORMAL TEMPERATURE CONDITIONS. INCLUDES
FLAMMABLE LIQUIDS WITH FLASH POINTS BELOW 73 F AND
BOILING POINTS ABOVE 100 F. AS WELL AS LIQUIDS WITH
FLASH POINTS BETWEEN 73 F AND 100 F.
(CLASSES IB & IC)
PHYSICAL 0 MINIMAL HAZARD - MATERIALS THAT ARE NORMALLY STABLE,
EVEN UNDER FIRE CONDITIONS, AND WILL NOT REACT WITH
WATER, POLYMERIZE, DECOMPOSE, CONDENSE, OR
SELF-REACT. NON-EXPLOSIVES.
PERSONAL PROTECTION H
H - SPLASH GOGGLES, GLOVES, SYNTHETIC APRON, VAPOR RESPIRATOR
SDS US LABCHEM
INFORMATION IN THIS SDS IS FROM AVAILABLE PUBLISHED SOURCES AND IS BELIEVED
TO BE ACCURATE. NO WARRANTY, EXPRESS OR IMPLIED, IS MADE AND LABCHEM INC
ASSUMES NO LIABILITY RESULTING FROM THE USE OF THIS SDS. THE USER MUST
DETERMINE SUITABILITY OF THIS INFORMATION FOR HIS APPLICATION.
EN (ENGLISH US)